Skip to main content
. 2020 Jul;18(7):636–654. doi: 10.2174/1570159X18666200114125628

Table 1.

Summary of nutraceuticals tested in LPS-induced mouse neuroinflammation model between 2016 and 2019.

Classification Nutraceuticals
Flavonoids
(Figure 1)
Anthocyanins [45-47]; Flavanones: Naringenin [50, 51], Hesperidin [57, 58], Eriodictyol [59, 60]; Flavanonols: Ampelopsin [62]; Flavonols: Kaempferol [64, 65], Quercetin [48, 67]; Icariin [68-71]; Flavanols: Proanthocyanidin [72]; Isoflavones: Tectorigenin [76], Icaritin [71]; Chalcones: Lonchocarpine [79].
Non-flavonoid Polyphenols
(Figure 2)
Stilbens: Resveratrol [22, 81]; Lignans/Lignins: Honokiol [82], Macranthol [84], Schizandrin [85]; Phenolic acids: Caffeic Acid [86], Chicoric Acid [89, 90]; Tannins: Punicalagin [92].
Terpenes
(Figure 3)
Triterpenes: Lupeol [31], Glycyrrhizic acid [97], Ginsenoside Rg3 [99], 3-Acetyl-11-Keto-Beta-Boswellic Acid [102], Gypenoside IX [104], Betulinic Acid [107]; Sesquiterpenoids: Aromatic-turmerone [109], Beta-elemene [110]; Tetraterpenes: Lycopene [112-114], Crocin [20]; Diterpenoids: Andrographolide [118, 119].
Glycosides
(Figure 4)
Saponin glycosides: Cantalasaponin [121], Astragaloside IV [123]; Flavonoid glycosides: Yuglanin [125], Baicalin [127].
Heterocyclic compounds
(Figure 5)
Alcaloids: Trigonelline [129]; Benzopyrans: Imperatorin [132], Esculetin [133,134]; Benzofurans: L-3-n-Butylphthalide [136]; Dioxoles: Sesamol [138]; Dioxolanes: Piperlongumine [140]; Xanthons: Alpha-mangostin [28].
Other aromatic compounds
(Figure 6)
Trans-cinnamaldehyde [144, 145], Curcumine [22, 145, 147], Beta-lapachone [27].
Organic acids
(Figure 6)
Methyl jasmonate [151-153], Ferulic Acid [155].
Organosulfur compounds
(Figure 6)
Sulforaphane [157-159]
Proteins Osmotin [160]
Lipids Scallop-derived plasmalogens [163]
Other compounds Xanthophylls (Fig. 6): Astaxathin [164, 165], Fucoxanthin [167].
Oils: Fish oil [168-170].