Table 2.

Neuroprotective strategies in stroke.

1. Glutamatergic activity inhibitors       1. Inhibition of presynaptic glutamate release       2. Postsynaptic inhibition of glutamate receptors   2. Ion channel modulators       1. Calcium-channel blockers       2. γ-Aminobutyric acid (GABA) modulators       3. Potassium channel activator   3. Antioxidants: Free radical scavengers   4. Anti-apoptotic agents   5. Anti-inflammatory agents   6. Other investigational therapies in cerebral ischemia       1. GPIIb/IIIa platelet inhibitor       2. Serotonin Agonists       3. Opioid receptor modulators       4. Matrix metalloproteinases (MMPs) inhibitors       5. Citicoline       6. Lubeluzole       7. Gangliosides       8. Growth factors       9. Albumin       10. Metal ion chelator       11. Ancrod       12. CEPO