Table 3.

Patient-reported quality-of-life assessments

				2-wk posttreatment difference from baseline
Assessment tool		Dose level		No.	Median (Min, Q1, Q3, Max)
EPIC-26: Bowel*		3.6 Gy × 15 fractions		6	−4.2 (−50.0, −20.8, 0, 8.3)
		4.7 Gy × 10 fractions		6	−33.3 (−87,5, −54.2, 0, 3.3)
		7.1 Gy × 5 fractions		12	−31.3 (−75.0, −54.2, −14.6, 8.3)
EPIC-26: Urinary irritative*		3.6 Gy × 15 fractions		6	−6.3 (−25, −18.8, 0, 6.3)
		4.7 Gy × 10 fractions		6	0 (−6.3, −6.3, 0, 12.5)
		7.1 Gy × 5 fractions		12	−6.3 (−56.3, −18.8, −3.1, 12.5)
EPIC-26: Urinary incontinence*		3.6 Gy × 15 fractions		6	4.1 (−12.5, −8.3, 8.3, 8.3)
		4.7 Gy × 10 fractions		6	3.1 (0, 0, 6.3, 14.5)
		7.1 Gy × 5 fractions		12	3.1 (−31.3, −11.5, 6.3, 62.8)
IPSS total score†		3.6 Gy × 15 fractions		6	2 (−3, −3, 7, 9)
		4.7 Gy × 10 fractions		6	1 (−1, −1, 3, 4)
		7.1 Gy × 5 fractions		12	2 (−3, 0, 3, 14)
6-wk posttreatment difference from baseline		10-wk posttreatment difference from baseline		6-mo posttreatment difference from baseline
No.	Median (Min, Q1, Q3, Max)	No.	Median (Min, Q1, Q3, Max)	No.	Median (Min, Q1, Q3, Max)
6	0 (−25.0, 0, 4.2, 8.3)	6	0 (−16.7, 0, 8.3, 8.3)	6	−2.1 (−4.2, −4.2, 8.3, 12.5)
6	−6.3 (−37.5, −25, 0, 12.5)	6	−2.1 (−25.0, −12.5, 0, 16.7)	6	−4.2 (−8.3, −8.3, 0, 0)
12	−16.7 (−50.0, −31.3, −2.1, 8.3)	11	−16.7 (−54,2, −20.8, 0, 8.3)	12	−6.3 (−41.7, −12.5, 0, 11.7)
6	−6.3 (−12.5, −6.3, −6.3, 31.3)	6	0 (−12.5, 0, 6.3, 37.5)	6	0 (−6.3, 0, 12.5, 37.5)
6	0 (−6.3, 0, 6.3, 18.8)	6	0 (−6.3, −6.3, 6.3, 25)	6	3.1 (0, 0, 6.3, 6.3)
12	−6.3 (−43.8, −12.5, 0, 6.3)	11	0 (−6.3, −6.3, 6.3, 25)	12	0 (−50, −6.3, 6.3, 25)
6	1 (−27, −12.5, 8.3, 33.3)	6	6.3 (0, 6.3, 22.8, 41.8)	6	0 (−33.3, −14.5, 45.8, 60.5)
6	0 (−8.3, −6.3, 6.3, 22.8)	6	1 (−14.5, 0, 6.3, 29)	6	−7.3 (−20.8, −16.8, 0, 0)
12	2 (−21, 0, 9.4, 35.8)	11	0 (−12.5, −6.3, 6.3, 27)	12	−3.1 (−21, −10.4, 21.9, 69)
6	2 (−7, −3, 5, 7)	6	−1.5 (−9, −7, 0, 2)	6	0.5 (−9, −6, 3, 4)
6	2 (−2, 0, 3, 3)	6	2 (−14, 0, 3, 4)	6	1 (−3, −1, 3, 3)
12	1 (−9, −2.5, 7.5, 14)	11	0 (−6, 0, 4, 9)	12	2 (−7, −2.5, 4.5, 18)

Abbreviations: EPIC = Expanded Prostate Cancer Index; IPSS = International Prostate Symptom Score; max = maximum; Min = minimum.

^*EPIC-26 (range 0–100). The higher the score, the better the patient is doing.

^†IPSS (range 0–35). Scores 1 to 7 = mild, 8 to 19 = moderate, 20 to 35 = severe prostate symptoms.