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. Author manuscript; available in PMC: 2020 Oct 1.
Published in final edited form as: J Pathol. 2019 Jul 8;249(2):206–214. doi: 10.1002/path.5308

Figure 2. Representative examples of ovarian endosalpingiosis in Ovgp1-iCreERT2;R26RLSL-eYFP mice.

Figure 2.

Ovarian endosalpingiosis lesions (indicated by black stars), are usually located in the medulla near ovarian hilum (A), but are occasionally found in the ovarian cortex (B). Some ovaries harbor more than one lesion (C). The epithelium lining endosalpingiotic glands and cysts is OVGP1 positive (inset) and includes both secretory and ciliated cells (D), with ciliated cells expressing tubulin (E) and secretory cells preferentially expressing PAX8 (F, inset shows high-magnification). Note the internal positive control for PAX8 (normal oviduct) in lower left corner of panel F at black arrow. Black arrowheads indicate ciliated cells in panels D and E. Scale bars: 200 μm (panels A, B, F); 100 μm (panel C); 50 μm (panels D, E).