Table 1.

Utilities and costs of health states and events.

Health states	Utility, annual	(SE)			Related healthcare costs		Patient and family costs		Intersectoral costsa
Stable CAD	0.671	(0.046)	20		€134	25	€0		€0
Mild PAD,	0.681	NA			€508	34	€423	34	€268	35
Moderate PAD	0.607	NA			€863	34	€358	34	€268	35
Severe PAD	0.430	(0.108)	23		€3551	24	€358	34	€268	35
CV events	CAD and mild PADb				CAD and mild PADc		CAD and PAD
Acute MI: 0–3, 4–6 months	0.603	(0.022)	20		€6630	28	€154	36,d	€1255	36
Sub-acute MI 7–9, 10–12 months	0.671	(0.046)	20		€2841	28	€33	36,d	€0
Post MI 12+ months	0.671	(0.046)	20		€287	28	€0		€0
Acute stroke, 0–3 months	0.523	(0.019)	20		€7440	28	€4742	30	€1212	36
Sub-acute stroke, 4–6 months	0.542	(0.044)	20		€7440	28	€4742	30	€1212	36
Sub-acute stroke 7–9, 10–12 months	0.542	(0.044)	20		€3189	28	€1666	30	€0
Post stroke 12+ months	0.542	(0.044)	20		€2776	28	€0		€0
Events	Decrement (SE)				Per event
Recurrent MI	0.063	(0.013)		21	€6630	28
Recurrent stroke	0.117	(0.035)		21	€7440	28
Major bleeding	0.047	(0.001)		16	€7819	32
Minor bleedinge	0.039	(0.003)		16	€200	33
Peripheral revascularisation	0.133	(0.002)		24	€3454	35
Amputation	0.161	(0.032)		24	€15,127	23
CV death					€6630
Non-CV death					€1227	31
Components PAD utilities	Utility	(SE)
General population aged 65+ years (mild)	0.870	(0.001)		21
Rutherford 1–3 (mild, moderate)	0.620	(0.155)		22
Rutherford 4 (moderate)	0.490	(0.123)		22
CV event with PAD	Decrement (SE)
Acute MI, 0–3, 4–6 months	0.063	(0.013)		20
Sub-acute, post MI, 7+ months	0	assumed
Acute stroke, 0–3 months	0.117	(0.041)		20
Sub-acute, post stroke, 4+ months	0.067	(0.025)		20

CAD: coronary artery disease; CV: cardiovascular; HS: haemorrhagic stroke; IS: ischaemic stroke; MI: myocardial infarction; PAD: peripheral arterial disease; SE: standard error.

^aCost of missed work, assumed to be unpaid for this retired population. A day of missed work is assumed to contain 3 hours of unpaid work, as seen in patients with rheumatoid arthritis.³⁸

^bFor PAD utilities with CV events: apply ‘CV event with PAD’ decrement to mild/moderate/severe PAD utility.

^cFor PAD-related healthcare costs with CV events: add moderate/severe PAD costs to the costs of CV event with CAD/mild PAD.

^dAssuming the number of healthcare visits (GP, specialist, etc.) is equal to patients post stroke.

^eDisutility of minor bleed assumed to last one month.