Table 2.
Frequency of different exposures during the observation period in cases and controls.
| Registered diagnosis code one year prior to index date (ICD-10 code)* and number of registered codes per individual | IIH (N = 902) n (%) | GP controls (N = 4510) n (%) | Obese controls (N = 4510) n (%) |
|---|---|---|---|
| All infectious or inflammatory disorders: | |||
| Summary: | 179 (20) | 258 (5.7) | 397 (8.8) |
| 1 | 94 (10) | 169 (3.8) | 252 (5.6) |
| 2 | 38 (4.2) | 56 (1.2) | 72 (1.6) |
| 3+ | 47 (5.2) | 33 (0.7) | 73 (1.6) |
| All infectious disorders: | |||
| Total exposed: | 121 (13) | 148 (3.3) | 252 (5.6) |
| 1 | 73 (8.1) | 121 (2.7) | 182 (4.0) |
| 2 | 33(3.7) | 16 (0.4) | 45 (1.0) |
| 3+ | 15 (1.7) | 11(0.2) | 25 (0.6) |
| All inflammatory disorders: | |||
| Total exposed: | 80 (8.9) | 127 (2.8) | 177 (3.9) |
| 1 | 39 (4.3) | 71 (1.6) | 107 (2.4) |
| 2 | 17 (1.9) | 35 (0.8) | 29 (0.6) |
| 3+ | 24 (2.7) | 21 (0.5) | 41 (0.9) |
| Specific infectious disorders (A+B diagnosis codes): | |||
| Total exposed: | 71 (7.9) | 86 (1.9) | 130 (2.9) |
| 1 | 48 (5.3) | 74 (1.6) | 99 (2.2) |
| 2 | 17 (1.9) | 6 (0.1) | 20 (0.4) |
| 3+ | 6 (0.7) | 6 (0.1) | 11 (0.2) |
| Respiratory inflammatory/infections: | |||
| Total exposed: | 56 (6.2) | 63 (1.4) | 116 (2.6) |
| 1 | 34 (3.8) | 47 (1.0) | 86 (1.9) |
| 2 | 13 (1.4) | 13 (0.3) | 18 (0.4) |
| 3+ | 9 (1.0) | 3 (0.1) | 12 (0.3) |
| Kidney inflammation/infections: | |||
| Total exposed: | 7 (0.8) | 8 (0.2) | 16 (0.4) |
| 1 | 5 (0.6) | 8 (0.2) | 15 (0.3) |
| 2 | 1 (0.1) | 0 (0) | 1 (0.0) |
| 3+ | 1 (0.1) | 0 (0) | 0 (0) |
| Female genital inflammation/infections: | |||
| Total exposed: | 18 (2.4) | 73 (1.9) | 83 (2.2) |
| 1 | 13 (1.4) | 64 (1.4) | 66 (1.5) |
| 2 | 4 (0.4) | 9 (0.2) | 15 (0.3) |
| 3+ | 1 (0.1) | 0 (0) | 2 (0.0) |
| GI inflammation/infections: | |||
| Total exposed: | 39 (4.3) | 51 (1.1) | 125 (2.8) |
| 1 | 22 (2.4) | 33 (0.7) | 78 (1.7) |
| 2 | 5 (0.6) | 7 (0.2) | 27 (0.6) |
| 3+ | 12 (1.3) | 11 (0.2) | 20 (0.4) |
| Skin inflammation/infections: | |||
| Total exposed: | 20 (2.2) | 53 (1.2) | 78 (1.7) |
| 1 | 17 (1.9) | 33 (0.7) | 55 (1.2) |
| 2 | 0 (0) | 11 (0.2) | 14 (0.3) |
| 3+ | 3 (0.3) | 9 (0.2) | 9 (0.2) |
| Inflammatory systemic disorder: | |||
| Total exposed: | 27 (3.0) | 25 (0.6) | 39 (0.9) |
| 1 | 8 (0.9) | 8 (0.2) | 10 (0.2) |
| 2 | 7 (0.8) | 11 (0.2) | 9 (0.2) |
| 3+ | 12 (1.3) | 6 (0.1) | 20 (0.4) |
*Includes both repeated codes on the same diagnosis or different diagnoses including within the examined diagnostic group.
IIH: idiopathic intracranial hypertension; GP controls: matched general population controls; obese controls: matched obese controls.Bold figures are the summary of the numbers of having 1 code registered, 2 codes registered or 3 or more codes registered in the preceding year.