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Perinatal exposure to bisphenols disrupts intestinal and systemic humoral responses in adult offspring dependent of bisphenol’s molecule. Plasma IgG (a) and IgA (b) concentrations measured by ELISA in female offspring mice at PND70. IgG (c) and IgA (d) specificity against E. coli lysate assessed in plasma by ELISA after normalizing to Ig concentrations. The lines represent the median (the 50th percentile). * P < 0.05; ** P < 0.01; **** P < 0.0001 vs. vehicle group. n = 5–14
