Table 1.
Comparison between survivors and non-survivors
| Survivors (n = 20) | Non-survivors (n = 14) | |||||||||||
| Demographics | ||||||||||||
| Age, median (IQR) (years) | 63.5 (24–72.5) | 63.5 (24–74) | ||||||||||
| Male (%) | 12 (60%) | 12 (85.7%) | ||||||||||
| BMI, median (IQR) Kg/m2 | 22.23 (15.4–22.8) | 22.74 (18.61–22.07) | ||||||||||
| Clinical severity | ||||||||||||
| APACHE II, mean (SD) | 27.5 ± 6.1 | 27.9 ± 9.3 | ||||||||||
| SOFA, mean (SD) | 13.8 ± 2.8 | 15.1 ± 2.5 | ||||||||||
| mNUTRIC, mean (SD) | 6.25 ± 1.61 | 6.21 ± 1.25 | ||||||||||
| SGA, median (IQR) | 6 (3–6) | 5 (1–5) | ||||||||||
| Vasopressor use (%) | 12 (60%) | 11 (78.6%) | ||||||||||
| Time to initiate feeding, median (range), hours | 8.16 (3–45.1) | 6.62 (3–23.25) | ||||||||||
| Comorbidities | ||||||||||||
| Diabetes mellitus (%) | 10 (50%) | 4 (28.6%) | ||||||||||
| Ischemic heart disease (%) | 5 (25%) | 4 (28.6%) | ||||||||||
| Cerebrovascular accident (%) | 5 (25%) | 1 (7.1%) | ||||||||||
| Chronic liver disease (%) | 3 (15%) | 1 (7.1%) | ||||||||||
| Chronic kidney disease (%) | 7 (35%) | 3 (21.4%) | ||||||||||
| Malignancy (%) | 2 (10%) | 3 (21.4%) | ||||||||||
| Connective tissue disease (%) | 5 (25%) | 4 (28.6%) | ||||||||||
| Diagnosis | ||||||||||||
| Pneumonia | 8 (40%) | 8 (57.1%) | ||||||||||
| Line sepsis | 2 (10%) | 1 (7.1%) | ||||||||||
| Other sites of sepsis | 10 (50%) | 5 (35.7%) | ||||||||||
| Details of calories and macronutrient delivered | ||||||||||||
| Total | Day 1 | Day 2 | Day 3 | Day 4 | Day 5 | Total | Day 1 | Day 2 | Day 3 | Day 4 | Day 5 | |
| Calories delivered, median, IQR (kcal) | 4655.45 (3439.96–5716.79) | 821.01 (384.25–999.65) | 845.40 (669.03–1102.08) | 1072.22 (815.25–1329.05) | 953.37 (817.38–1281.80) | 1139.75 (1028.50–1421.00) | 4600.76 (3754.91–6067.63) | 590.71 (330.82–896.00) | 1038.65 (637.48–1584.00) | 1143.54 (808.75–1620.66) | 941.25 (753.12–1419.75) | 1063.03 (76.25–1490.29) |
| Carbohydrates delivered, median, IQR (g) | 498.50 (379.50–646.00) | 51.58 (34.07–98.77) | 106.87 (69.52–117.94) | 117.93 (96.86–145.8) | 117 (109.33–129.6) | 126.22 (98.28–159.69) | 482.00 (400.00–581.00) | 35.21 (24.95–83.02) | 101.83 (62.24–129.6) | 103.53 (86.65–131.53) | 107.56 (86.4–125.95) | 107.56 (93.79–132.53) |
| Lipid delivered, median, IQR (g) | 190.50 (158.00–294.00) | 23.43 (10.59–52.17) | 55.61 (19.02–69.36) | 43.2 (34.38–69.33) | 43.2 (31.20–67.00) | 57.29* (47.52–69.33) | 154.50 (109.00–282.00) | 19.38 (7.60–28.62) | 36.47 (26.13–51.84) | 35.91 (23.10–53.72) | 34.62 (24.66–71.02) | 29.95* (25.01–55.95) |
| Protein delivered, median, IQR (g) | 323.74 (261.78–372.05) | 44.92 (25.49–66.47) | 61.17 (47.01–79.98) | 74.88 (55.2–86.84) | 66.36 (30.33–77.80) | 70.25 (62.59–91.15) | 279.33 (110.16–398.17) | 34.32 (34.32–17.41) | 69 (30.78–76.48) | 66.8 (47.66–86.14) | 61.91 (42.80–90.78) | 77.68 (43.22–88.32) |
Abbreviations: IQR interquartile range, BMI body mass index, APACHE Acute Physiology And Chronic Health Evaluation, SOFA sequential organ failure assessment, mNUTRIC modified Nutrition Risk in Critically ill, SGA Subjective Global Assessment, IC indirect calorimetry
*p = 0.02