Table 2.
Bivariate and multivariate cox regression analysis of preterm neonatal mortality admitted in FHSH, Bahir Dar, Ethiopia, from 1 August 2017 to 30 July 2018 (n = 584).
| Covariates | Category | Outcome number (%) |
HR 95% CI |
||
|---|---|---|---|---|---|
| Survival | Death | CHR | AHR | ||
| RDS | Yes | 92 (35.8%) | 165 (64.2%) | 3.01 (2.308, 3.926) | 1.771 (1.317, 2.382) |
| No | 245 (74.9%) | 82 (25.1%) | 1 | ||
| Sepsis | Yes | 299 (55.3%) | 242 (44.7%) | 3.222 (1.328, 7.814) | 1.777 (0.72, 4.386) |
| No | 38 (88.4%) | 5 (11.6%) | 1 | ||
| NEC | Yes | 17 (17.2%) | 82 (82.8%) | 2.068 (1.585, 2.699) | 1.848 (1.37, 2.492) |
| No | 320 (66%) | 165 (34%) | 1 | ||
| Meningitis | Yes | 19 (73.1%) | 7 (26.9%) | 0.372 (0.175, 0.791) | 0.53 (0.241, 1.164) |
| No | 318 (57%) | 240 (43%) | 1 | ||
| Hyperbilirubinemia | Yes | 117 (61.3%) | 74 (38.7%) | 0.627 (0.477, 0.824) | 0.581 (0.436, 0.775) |
| No | 220 (56%) | 173 (44%) | 1 | ||
| PNA | Stage III | 3 (33.3%) | 6 (66.7%) | 3.249 (1.1441, 7.327) | 2.459 (1.074, 5.634) |
| Stage II | 11 (40.7%) | 16 (59.3%) | 1.751 (1.053, 2.909) | 1.764 (1.039, 2.996) | |
| No | 323 (58.9%) | 225 (41.1%) | 1 | ||
| Anemia | Yes | 14 (41.2%) | 20 (58.8%) | 1.718 (1.086, 2.718) | 0.9 (0.552, 1.468) |
| No | 323 (58.7%) | 227 (41.3%) | 1 | ||
| HAI | Yes | 37 (53.6%) | 32 (46.4%) | 1.518 (1.038, 2.220) | 1.8 (1.206, 2.757) |
| No | 300 (58.3%) | 215 (41.7%) | 1 | ||
| Admission temperature (T°C) | Abnormal | 229 (53%) | 203 (47%) | 1.649 (1.19, 2.286) | 1.1 (0.815, 1.594) |
| Normal | 108 (71.1%) | 44 (28.9%) | 1 | ||
| GA | <28 | 0 (0%) | 15 (100%) | 13.388 (7.418, 24.164) | 2.394 (0.979, 5.856) |
| 28–31.9 | 39 (24.2%) | 122 (75.8%) | 4.926 (3.497, 6.939) | 2.367 (1.551, 3.612) | |
| 32–33.9 | 93 (58.9%) | 65 (41.1%) | 2.134 (1.457, 3.125) | 1.691 (1.133, 2.524) | |
| 34–36.9 | 205 (82%) | 45 (18%) | 1 | ||
| Birth weight | 600–999 | 0 (%) | 23 (100%) | 43.616 (10.246, 185.67) | 10.968 (2.235, 53.8) |
| 1000–1499 | 46 (26.3%) | 129 (73.7%) | 10.889 (2.691, 44.068) | 4.134 (0.977, 17.49) | |
| 1500–2499 | 263 (73.9%) | 93 (26.1%) | 3.698 (1.911, 15.021) | 2.354 (0.57, 9.723) | |
| 2500-3500 | 28 (93.3) | 2 (6.7%) | 1 | ||
| Place of delivery | Home | 11 (36.7%) | 19 (63.3%) | 2.381 (1.489, 3.806) | 2.08 (1.26, 3.434) |
| Institution | 326 (58.8%) | 228 (41.2%) | 1 | ||
FHSH: Felege Hiwot specialized hospital; HR: hazard ratio; CI: confidence interval; AHR: adjusted hazard ratio; CHR: crude hazard ratio; RDS: respiratory distress syndrome; GA: gestational age; NEC: necrotizing enterocolitis; PNA: perinatal asphyxia; HAI: hospital-acquired infection.