Table 3.
The Correlations Between GAST Expression and Other Clinical Features
| Clinical Features | No. Cases | GAST Expression | P-value | |
|---|---|---|---|---|
| High (%) | Low (%) | |||
| Gender | ||||
| Male | 121 | 74 (61.1) | 47 (38.9) | |
| Female | 38 | 18 (47.4) | 20 (52.6) | 0.187 |
| Age | ||||
| ≥60 | 74 | 43 (58.1) | 31 (41.9) | |
| <60 | 85 | 49 (57.6) | 36 (42.4) | 0.953 |
| Tumor site | ||||
| Cardiac cancer | 50 | 29 (58.0) | 21 (42.0) | |
| Non-cardiac cancer | 109 | 63 (57.8) | 46 (42.2) | 0.981 |
| Survival status | ||||
| Live | 75 | 29 (38.7) | 46 (61.3) | |
| Dead | 84 | 63 (75.0) | 21 (25.0) | <0.001 |
| Lauren’s classification | ||||
| Intestinal type | 67 | 42 (62.7) | 25 (37.3) | |
| Diffused type | 92 | 50 (54.3) | 42 (45.7) | 0.331 |
| TNM stage | ||||
| I | 18 | 6 (33.3) | 12 (66.7) | |
| II | 41 | 24 (58.5) | 17 (41.5) | |
| III | 91 | 55 (60.4) | 36 (39.6) | |
| IV | 9 | 7 (77.8) | 2 (22.2) | 0.114 |
| Tumor invasive depth (T) | ||||
| 1 | 8 | 3 (37.5) | 5 (62.5) | |
| 2 | 17 | 7 (41.2) | 10 (58.8) | |
| 3 | 69 | 37 (53.6) | 32 (46.4) | |
| 4 | 65 | 45 (69.2) | 20 (30.8) | 0.062 |
| Lymph node metastasis (N) | ||||
| 0 | 47 | 20 (42.6) | 27 (57.4) | |
| 1 | 22 | 17 (77.3) | 5 (22.7) | |
| 2 | 38 | 19 (50.0) | 19 (50.0) | |
| 3 | 52 | 36 (69.2) | 16 (30.8) | 0.008 |
| Distant metastasis (M) | ||||
| Yes | 9 | 7 (77.8) | 2 (22.2) | |
| No | 150 | 85 (56.7) | 65 (43.3) | 0.305 |
| p-STAT3 expression | ||||
| High | 97 | 64 (66.0) | 33 (34.0) | |
| Low | 62 | 28 (45.2) | 34 (54.8) | 0.013 |
| MMP11 expression | ||||
| High | 105 | 75 (71.4) | 30 (28.6) | |
| Low | 54 | 17 (31.5) | 37 (68.5) | <0.001 |