Table 2.
Top 10 Up- and Down-Regulated DEmRNAs and DEmiRNAs in CSCC
| mRNA | Combined.ES | p-value | FDR | Regulation |
|---|---|---|---|---|
| CDKN2A | 4.09523096 | 0 | 0 | Up |
| KNTC1 | 3.415615858 | 0 | 0 | Up |
| MCM2 | 3.262138669 | 0 | 0 | Up |
| DTL | 3.12448687 | 0 | 0 | Up |
| ECT2 | 2.932967572 | 0 | 0 | Up |
| SPAG5 | 2.87189987 | 0 | 0 | Up |
| RFC4 | 2.86851678 | 0 | 0 | Up |
| MCM6 | 2.863540309 | 0 | 0 | Up |
| KIF14 | 2.834991169 | 0 | 0 | Up |
| TIMELESS | 2.811416252 | 0 | 0 | Up |
| UPK1A | −3.938910321 | 0 | 0 | Down |
| CRNN | −3.484057128 | 0 | 0 | Down |
| ENDOU | −3.480046127 | 0 | 0 | Down |
| CRISP3 | −3.397031566 | 0 | 0 | Down |
| EDN3 | −3.051176288 | 0 | 0 | Down |
| MAL | −2.902463244 | 0 | 0 | Down |
| BBOX1 | −2.892847988 | 0 | 0 | Down |
| SLURP1 | −2.824556627 | 0 | 0 | Down |
| PPP1R3C | −2.691069042 | 0 | 0 | Down |
| DSG1 | −2.626794273 | 0 | 0 | Down |
| miRNA | ||||
| hsa-miR-106b-5p | 1.70322226 | 5.51E-05 | 0.00282703 | Up |
| hsa-miR-21-5p | 1.314433323 | 0.000352172 | 0.009039083 | Up |
| hsa-miR-18a-5p | 1.029429377 | 0.003619066 | 0.047549331 | Up |
| hsa-miR-142-3p | 1.019333791 | 0.003999802 | 0.047549331 | Up |
| hsa-miR-125b-5p | −1.753027386 | 6.34E-06 | 0.000507467 | Down |
| hsa-miR-203a-3p | −1.73909463 | 6.59E-06 | 0.000507467 | Down |
| hsa-miR-99a-5p | −1.414419027 | 0.00011931 | 0.004593453 | Down |
| hsa-miR-497-5p | −1.387732202 | 0.000150657 | 0.004640232 | Down |
| hsa-let-7c-5p | −1.168987104 | 0.001015067 | 0.022331465 | Down |
| hsa-miR-195-5p | −1.129936328 | 0.001989935 | 0.038306241 | Down |
| hsa-miR-100-5p | −1.059650819 | 0.002817986 | 0.047549331 | Down |
| hsa-miR-149-5p | −1.040611481 | 0.003198146 | 0.047549331 | Down |
| hsa-miR-199b-5p | −1.010825035 | 0.004013905 | 0.047549331 | Down |
Abbreviations: DEmRNAs, differentially expressed mRNAs; DEmiRNAs, differentially expressed miRNAs; ES, effect size; FDR, false discovery rate; CSCC, cervical squamous cell cancer.