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. 2020 Aug 28;8:e9434. doi: 10.7717/peerj.9434

Figure 4. Ultracentrifugation (UC) method co-isolates almost no proportion of free miRNAs.

Figure 4

(A-B) A high concentration (7 ×109 copies/µL) of cel-miR-39 was added in serum. Exosomes were extracted by the UC method. (A) The ratio of co-precipitated cel-miR-39 in different samples to standard sample (109 copies/µL cel-miR-39). (b) The amount of exosomal miR-126 and miR-152 in different samples. ∗∗p < 0.01, ∗∗∗p < 0.001 vs. Control. #p < 0.05 vs. RNase Inhibitor.