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Results obtained in the Morris Water Maze. A) Spatial learning as area under the curve (AUC) of latency to find the platform and B) spatial memory as the number of times mice swam over the previous position of the platform. C) Memory consolidation. D) AUC of latency to find the relocated platform in reversal learning. Note that although not statistically significant, all parameters indicate worse performance in 12-month-old vaccinated compared to mock treated mice.
