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. 2020 May 14;9(1):1760685. doi: 10.1080/2162402X.2020.1760685

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© 2020 The Author(s). Published with license by Taylor & Francis Group, LLC.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 2. — AXT201 inhibits the growth of NT4 and 4T1 tumors in mice. (a) Schematic showing dosing schedule. The blue arrow indicates the start of daily peptide injections from day 2 on. The dashed lines indicate deviations in survival and growth experiments from flow experiments, which were terminated on day 17. (b, c) Tumor growth of water- (blue) and AXT201-treated (orange) 4T1 tumors showing both averages over time (b) and individual tumor measurements from Day 22 (c). *** indicates p < .001, two-way ANOVA with Bonferroni posttest. (d-f) Tumor growth of water- (blue) and AXT201-treated (orange) NT4 tumors showing both averages over time (d) and individual tumor measurements from Day 38 (e). * indicates p < .05, two-way ANOVA with Bonferroni posttest. (f) Kaplan-Meier curve showing differences in survival for water- and AXT201-treated mice. * indicates p < .05, Log-Rank Test.