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The effects of AXT201 on myeloid cell populations in 4T1 tumors. (a-f) Subpopulations of various CD11b+ (myeloid) cells isolated from whole 4T1 tumors treated with water or AXT201 relative to (a, c, and f) total live cell, (b) total CD11b+ cells, and (d) total macrophages. Targets include (a) total myeloid cells, (b and c) macrophages, (d) Arginase-1 expressing macrophages, (e) normalized M-MDSCs, and (f) PMN-MDSCs. N ≥ 11, *p < .05, Student’s t-test or Mann-Whitney test.
