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Association of signature 1 with tumor mutation burden in pooled TNBC cohort.
Tumor mutation burden (a) and neoantigen burden (b) were stratified by mutational signature 1. (c) Multivariate logistic regression analysis of signature 1 mutation with TMB after adjusted for age, grade, histological type, lymph node, mutational signatures, and mutations in BRCA1/2 and ATR. Square data markers indicated estimated hazard ratios. Error bars represent 95% CIs.
