Table 3. Seasonality of ACS versus CLI by region.
| Region | Peak-to-trough ratio | (P value versus ACS) | Peak month | (P value versus ACS) | |
|---|---|---|---|---|---|
| Hokkaido region | ACS CLI |
1.15 [1.12 to 1.20] 1.43 [1.30 to 1.57] |
--- (P < 0.001) |
2.06 [1.62 to 2.51] 2.22 [1.70 to 2.75] |
--- (P = 0.62) |
| Tohoku region | ACS CLI |
1.17 [1.14 to 1.21] 1.43 [1.26 to 1.64] |
--- (P = 0.002) |
1.64 [1.25 to 2.03] 2.96 [2.21 to 3.65] |
--- (P = 0.048) |
| Kanto-Koshinetsu region | ACS CLI |
1.22 [1.20 to 1.23] 1.65 [1.58 to 1.73] |
--- (P < 0.001) |
1.34 [1.21 to 1.46] 2.94 [2.76 to 3.11] |
--- (P < 0.001) |
| Tokai-Hokuriku region | ACS CLI |
1.23 [1.20 to 1.26] 2.13 [1.96 to 2.33] |
--- (P < 0.001) |
1.38 [1.18 to 1.57] 2.80 [2.57 to 3.04] |
--- (P = 0.005) |
| Kinki region | ACS CLI |
1.24 [1.22 to 1.27] 1.85 [1.76 to 1.95] |
--- (P < 0.001) |
1.20 [1.04 to 1.36] 2.60 [2.44 to 2.77] |
--- (P = 0.021) |
| Chugoku-Shikoku region | ACS CLI |
1.19 [1.16 to 1.22] 1.92 [1.71 to 2.15] |
--- (P < 0.001) |
1.33 [1.04 to 1.62] 2.44 [2.12 to 2.77] |
--- (P = 0.17) |
| Kyushu-Okinawa region | ACS CLI |
1.20 [1.17 to 1.22] 1.97 [1.82 to 2.14] |
--- (P < 0.001) |
1.38 [1.14 to 1.61] 2.83 [2.58 to 3.07] |
--- (P = 0.002) |
Data represent estimates and 95% CIs. P values for peak-to-trough ratio and volume on weekends are versus ACS in the same region. The month coded as 1 to 12 indicates January to December. ACS, acute coronary syndrome; CLI, critical limb ischemia.