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. 2020 Jul 20;295(35):12545–12558. doi: 10.1074/jbc.RA120.012792

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© 2020 Ahmad et al.

Published under exclusive license by The American Society for Biochemistry and Molecular Biology, Inc.

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Figure 5. — VDR activation increases Slc30a10 mRNA levels in vivo. A and B, expression of Slc30a10 (A) and Slc39a8 (B) in the liver and gastrointestinal tissues in C57BL/6 mice (n = 7). The liver was used as a reference tissue. C–E, ileal expression of Slc30a10 (C), VDR targets Cyp24a1 and S100g (D), and Slc39a8 (E) after oral gavage with corn oil supplemented with vehicle, LCA, calcitriol, or CA. n = 5–7 mice/group. F, Slc30a10 expression in the liver, duodenum, and jejunum after gavage experiment. Full result tables of one-way ANOVA and post-hoc pairwise comparisons are shown in Table S8. *, p < 0.05; ***, p < 0.001. Error bars, S.D.