Table 2.
Associations Between Receiving at Least One Dose of the HPV Vaccine and Physical and Mental Health Complaints 6 Months Prior to Survey Among Girls in Secondary Education Institutions in Denmark (N = 41,333)
| Complaints | Vaccination status | Number of girls who reported the complaint (%) | Crude model OR (95% CI) | Partially adjusted model* OR (95% CI) | Fully adjusted model† OR (95% CI) |
|---|---|---|---|---|---|
| Headache | Vaccinated | 27,769 (72.4) | 0.96 (0.86–1.05) | 0.95 (0.86–1.06) | 0.93 (0.82–1.04) |
| Unvaccinated | 1547 (73.6) | 1.0 (ref) | 1.0 (ref) | 1.0 (ref) | |
| Stomachache | Vaccinated | 18,913 (49.6) | 0.97 (0.89–1.06) | 1.02 (0.93–1.11) | 1.02 (0.92–1.13) |
| Unvaccinated | 1056 (50.4) | 1.0 (ref) | 1.0 (ref) | 1.0 (ref) | |
| Menstrual cramps | Vaccinated | 28,908 (75.5) | 0.96 (0.87–1.07) | 1.02 (0.92–1.14) | 0.97 (0.86–1.09) |
| Unvaccinated | 1603 (76.1) | 1.0 (ref) | 1.0 (ref) | 1.0 (ref) | |
| Neck pain | Vaccinated | 23,482 (61.5) | 1.00 (0.92–1.10) | 1.02 (0.93–1.12) | 1.04 (0.94–1.15) |
| Unvaccinated | 1286 (61.3) | 1.0 (ref) | 1.0 (ref) | 1.0 (ref) | |
| Sore throat | Vaccinated | 19,302 (50.6) | 0.89 (0.81–0.97) | 0.89 (0.81–0.97) | 0.86 (0.78–0.95) |
| Unvaccinated | 1125 (53.5) | 1.0 (ref) | 1.0 (ref) | 1.0 (ref) | |
| Been sad | Vaccinated | 28,113 (73.4) | 0.92 (0.83–1.02) | 0.89 (0.80–0.99) | 0.86 (0.76–0.97) |
| Unvaccinated | 1580 (75.9) | 1.0 (ref) | 1.0 (ref) | 1.0 (ref) | |
| Been irritable/bad mood | Vaccinated | 33,812 (88.2) | 1.19 (1.05–1.36) | 1.09 (0.96–1.25) | 1.04 (0.88–1.22) |
| Unvaccinated | 1816 (86.2) | 1.0 (ref) | 1.0 (ref) | 1.0 (ref) | |
| Been nervous | Vaccinated | 26,487 (69.2) | 0.99 (0.91–1.10) | 0.98 (0.89–1.08) | 0.95 (0.85–1.06) |
| Unvaccinated | 1460 (69.3) | 1.0 (ref) | 1.0 (ref) | 1.0 (ref) | |
| Had sleep problems | Vaccinated | 21,552 (56.3) | 0.93 (0.85–1.02) | 0.97 (0.88–1.06) | 0.96 (0.86–1.06) |
| Unvaccinated | 1218 (58.0) | 1.0 (ref) | 1.0 (ref) | 1.0 (ref) |
Legend: *Adjusted for age, ethnicity, type of school and living arrangements; †adjusted for variables in partially adjusted model and health behaviors (smoking, alcohol use, drug use and physical activity)