Table 2.

Steps in Computing Adherence

Step 1		Step 2	Step 3	Step 4	Step 5	Step 6
Day in time period (t) (12:00:00 a.m.–11:59:59 p.m.)	“Taken” doses per EAMD	Number of doses taken per day (N)	Number of prescribed doses per day* (P)	Daily summary statistic $\left(\frac{N}{P}\times 100\right)$	Daily summary statistic with upper limit imposed	Daily summary statistic with periods of nonuse removed
Sun 10/27/2019	10:19:05 p.m.	1	1	100%	100%	100%
Mon 10/28/2019		0	1	0%	0%	‡
Tue 10/29/2019	9:24:18 p.m.	1	1	100%	100%	100%
Wed 10/30/2019	9:38:31 p.m.	1	1	100%	100%	100%
Thu 10/31/2019	8:55:28 p.m.	1	1	100%	100%	100%
Fri 11/01/2019		0	1	0%	0%	0%
Sat 11/02/2019	12:07:24 a.m. 9:02:15 p.m.	2	1	200%	100%†	100%
			Step 7: adherence $\left(\frac{100\%+100\%+100\%+100\%+0\%+100\%}{6}\right)$			83%

EAMD electronic adherence monitoring device

*Prescribed medication regimen includes a once daily medication

†Range of 0–100% imposed such that values > 100% were recoded to 100%

‡Value removed as patient took their medication during a day hospital visit and not from the EAMD