Table 2.

Summary one-way ANOVA and Bonferroni’s multiple comparisons tests results.

Parameter	FEP	Risperidone	Olanzapine	Aripiprazole	Clozapine	Controls
Plasma levels (relative units)
β-III tubulin	1.12 ± 0.24	1.34 ± 0.22	1.34 ± 0.37	1.34 ± 0.67	1.58 ± 0.35	1.00 ± 0.30
P value Bonferroni post-hoc test	> 0.9999	0.0751	0.0837	0.0766	0.0001*
One-way ANOVA	F(5,76) = 5.437 P = 0.0002*
Nf-L	1.08 ± 0.72	1.22 ± 0.19	1.21 ± 0.27	1.22 ± 0.30	1.52 ± 0.41	1.00 ± 0.40
P value Bonferroni post-hoc test	> 0.9999	0.9370	0.9370	0.9371	0.0071*
One-way ANOVA	F(5,76) = 2.469 P = 0.0403*
GFAP	1.07 ± 0.59	1.20 ± 0.64	1.20 ± 0.21	1.21 ± 0.41	1.51 ± 0.57	1.00 ± 0.37
P value Bonferroni post-hoc test	> 0.9999	> 0.9999	> 0.9999	> 0.9999	0.0151*
One-way ANOVA	F(5,76) = 2.077 P = 0.0781
Ratio
Neutrophils/lymphocytes	2.59 ± 2.06	2.27 ± 0,96	2.59 ± 1.05	1.81 ± 0.66	4.96 ± 6.59	3.26 ± 3.45
P value Bonferroni post-hoc test	> 0.9999	> 0.9999	> 0.9999	> 0.9999	0.9162
One-way ANOVA	F(5,76) = 0.9717 P = 0.4406

One-way ANOVA followed by Bonferroni post-hoc test: comparison of patient’s groups with control group.

FEP first-episode psychosis, Nf-L neurofilament light chain, GFAP glial fibrillary acidic protein.

*Statistical significance: P ≤ 0.05.