Table 3.
Diagnostic accuracy of procalcitonin, C-reactive protein, white blood cells, and proportion of neutrophils for the diagnosis of infection in liver failure
Cut offs | Sensitivity (%) | Specificity (%) | PLR | NLR | PPV (%) | NPV (%) | P value | AUROC | |
PCT | ≥ 1.01 | 42.60 | 78.80 | 2.01 | 0.73 | 61.01 | 63.81 | < 0.0001 | 0.637 |
CRP | ≥ 17.5 | 63.91 | 67.28 | 1.95 | 0.54 | 60.33 | 70.54 | < 0.0001 | 0.692 |
WBC | ≥ 7.90 | 47.93 | 79.72 | 2.36 | 2.36 | 64.79 | 66.28 | < 0.0001 | 0.638 |
N% | ≥ 73.8 | 55.03 | 76.50 | 2.34 | 0.59 | 64.58 | 68.60 | < 0.0001 | 0.674 |
PCT: Procalcitonin; CRP: C-reactive protein; WBC: White blood cell count; N%: Proportion of neutrophils; PLR: Positive likelihood ratio; NLR: Negative likelihood ratio; PPV: Positive predictive value; NPV: Negative predictive value; AUROC: Area under the receiver operating characteristic curve.