Table 5.
The comparison of human leukocyte antigen alleles which increase or decrease the gastric cancer/duodenal ulcer risk in gastric cancer and duodenal ulcer subgroups in terms of CagA+(≥ 2) EPIYA-C, n (%)
GC (≥ 2) EPIYA-C (n = 26, alleles=52) | DU (≥ 2) EPIYA-C (n = 14, alleles=28) | OR | 95%CI | P value | |||
Minimum | Maximum | ||||||
HLA-A*02 | 12 (23) | 10 (36) | 0.54 | 0.19 | 1.47 | 0.2302 | |
HLA-B*35 | 12 (23) | 4 (14) | 1.80 | 0.52 | 6.21 | 0.3527 | |
HLA-DRB1*13 | 12 (23) | 6 (21) | 1.10 | 0.36 | 3.83 | 0.8663 | |
HLA-DQA1*01 | 24 (46) | 10 (36) | 1.54 | 0.59 | 3.97 | 0.3689 | |
HLA-DRB1*06 | 12 (23) | 8 (28) | 0.75 | 0.26 | 2.12 | 0.5889 |
HLA: Human leukocyte antigen; GC: Gastric cancer; DU: Duodenal ulcer; CI: Confidence interval; OR: Odds ratio.