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The chemical structures of a indirect inhibitors (UFH, LMWHs, and warfarin) and b direct inhibitors of thrombin (bivalirudin, dabigatran etexilate, and argatroban). UFH, LMWHs, bivalirudin, and argatroban are parenterally used anticoagulants, whereas warfarin and dabigatran etexilate are orally used anticoagulants. Argatroban is the focus of this review
