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. 2020 Aug 31;10:14275. doi: 10.1038/s41598-020-71251-z

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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A representative patient with chronic hypertension with severe retinal microvascular rarefaction in the superficial vascular plexus (SVP) but relatively good vessel density in the deep vascular plexus (DVP). (A,B) Optical coherence tomography angiography (OCTA) images of the SVP and DVP. (C,D) are the vessel density maps of the SVP and DVP. (E) B-scan shows the segmentation boundaries of SVP and (F) boundaries of DVP. (G) Color fundus photo shows mild tortuous retinal vessels.