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Schematic illustrating mechanisms of fucoidan-mediated intracellular signaling through SR-A and TLR-4. Abbreviations in figure: PERK—protein kinase R-like ER kinase; IFN-β—interferon-β; CHOP—C/EBP-homologous protein; mTOR—mammalian target of rapamycin; IRF-3—interferon regulatory factor 3; ROS—reactive oxygen species; AKT—protein kinase B.
