Table 2.
Summary of topological indexes used to evaluate the centrality of each candidate TF in the reconstructed gene regulatory network.
| TF (Cluster) | Degree | Betweenness Centrality | Radiality |
|---|---|---|---|
| SPIB (M3) | 104 | 0.36 | 3.41 |
| NFKB1 (M2) | 91 | 0.22 | 3.24 |
| TBP (M1) | 74 | 0.14 | 3.02 |
| BCL6 (M5) | 55 | 0.08 | 2.77 |
| SRF (M4) | 53 | 0.08 | 2.75 |
| CEBPE (M8) | 50 | 0.08 | 2.71 |
| PAX3 (M6) | 48 | 0.05 | 2.68 |
| ATF2 (M7) | 46 | 0.06 | 2.65 |
| CHD1 (T1) | 29 | 0.04 | 2.43 |
Candidate transcription factors (TFs) of each cluster are ranked by degree. The selected “hub” TFs are highlighted with bold characters.