Table 3.
IHC staining intensity and proportion of positive stained tumor cells for E-cadherin, vimentin, OPN and OPN-c in OC.
| Cases Analyzed (n = 49) |
E-cadherin | Vimentin | Cytoplasm OPN | Membrane OPN | Nuclear OPN-c | Cytoplasm OPN-c |
|---|---|---|---|---|---|---|
| Proportion of positive stained cells | ||||||
| <5% | 7 (14.3%) | 30 (61.2%) | 28 (57.1%) | 37 (75.5%) | 2 (4.1%) | 23 (47.0%) |
| 5–25% | 5 (10.2%) | 11 (22.4%) | 6 (12.2%) | 3 (6.1%) | 5 (10.2%) | 4 (8.2%) |
| 25–50% | 5 (10.2%) | 2 (4.1%) | 6 (12.2%) | 4 (8.2%) | 3 (6.1%) | 5 (10.2%) |
| 50–75% | 7 (14.3%) | 1 (2.0%) | 5 (10.2%) | 4 (8.2%) | 7 (14.3%) | 8 (16.3%) |
| >75% | 25 (51.0%) | 5 (10.2%) | 4 (8.2%) | 1 (2.0%) | 32 (65.3%) | 9 (18.4%) |
| Staining intensity | ||||||
| Absent | 5 (10.2%) | 21 (42.9%) | 17 (34.7%) | 29 (59.2%) | 2 (4.1%) | 21 (42.9%) |
| Faint | 8 (16.3%) | 1 (2.0%) | 13 (26.5%) | 2 (4.1%) | 17 (34.7%) | 16 (32.7%) |
| Moderate | 16 (32.7%) | 8 (16.3%) | 14 (28.6%) | 5 (10.2%) | 15 (30.6%) | 9 (18.4%) |
| Strong | 20 (40.9%) | 19 (38.8%) | 5 (10.2%) | 13 (26.4%) | 15 (30.6%) | 3 (6.1%) |
| Staining Score | ||||||
| 0 | 5 (10.2%) | 21 (42.9%) | 17 (34.7%) | 29 (59.2%) | 2 (4.1%) | 21 (42.9%) |
| 1 | 1 (2.0%) | 0 (0.0%) | 8 (16.3%) | 2 (4.1%) | 0 (0.0%) | 2 (4.1%) |
| 2 | 3 (6.1%) | 5 (10.2%) | 3 (6.1%) | 2 (4.1%) | 5 (10.2%) | 3 (6.1%) |
| 3 | 3 (6.1%) | 7 (14.3%) | 8 (16.3%) | 5 (10.2%) | 0 (0.0%) | 4 (8.2%) |
| 4 | 7 (14.3%) | 9 (18.4%) | 4 (8.2%) | 3 (6.1%) | 6 (12.2%) | 6 (12.2%) |
| 5 | 5 (10.2%) | 1 (2.0%) | 4 (8.2%) | 4 (8.2%) | 9 (18.4%) | 8 (16.3%) |
| 6 | 8 (16.3%) | 2 (4.1%) | 4 (8.2%) | 3 (6.1%) | 12 (24.5%) | 2 (4.1%) |
| 7 | 17 (34.7%) | 4 (8.2%) | 1 (2.0%) | 1 (2.0%) | 15 (30.6%) | 3 (6.1%) |