TABLE 2.
Genes predicted in the PLAHV genome
Gene | Product | Positions | Orientationa | % amino acid sequence identity to: |
|
---|---|---|---|---|---|
PtAHV1 | HSV-1 | ||||
RL1 | ICP34.5 | 1405–2292 | + | 80.4 | 34.6 |
RL2 | Ubiquitin E3 ligase; ICP0 | + | Not calculated | 17.6 | |
Exon 1 | 3297–3686 | Not calculated | Not calculated | ||
Exon 2 | 4936–5529 | Not calculated | Not calculated | ||
UL1 | Envelope glycoprotein L | 7226–7933 | + | 74.6 | 36.6 |
UL2 | Uracil-DNA glycosylase | 8328–8990 | + | 89.1 | 46.4 |
UL3 | Nuclear protein | 9074–9742 | + | 82.9 | 53.8 |
UL4 | Nuclear protein | 9789–10421 | − | 89.7 | 44.4 |
UL5 | Helicase-primase helicase subunit | 10455–13076 | − | 95.1 | 78.4 |
UL6 | Capsid portal protein | 13075–15120 | + | 94.0 | 64.1 |
UL7 | Tegument protein | 15071–15958 | + | 92.9 | 61.1 |
UL8 | Helicase-primase subunit | 16077–18083 | − | 77.8 | 42.8 |
UL9 | DNA replication origin-binding helicase | 18436–20985 | − | 96.7 | 78.0 |
UL10 | Envelope glycoprotein M | 20942–22297 | + | 94.9 | 58.3 |
UL11 | Myristylated tegument protein | 22917–23174 | − | 88.2 | 44.8 |
UL12 | DNase | 23099–25069 | − | 80.4 | 50.4 |
UL13 | Tegument serine/threonine protein kinase | 25072–26619 | − | 96.7 | 66.2 |
UL14 | Tegument protein | 26379–26891 | − | 90.6 | 49.5 |
UL15 | DNA packaging terminase subunit 1 | + | 97.3 | 82.7 | |
Exon 1 | 27110–28135 | Not calculated | Not calculated | ||
Exon 2 | 31526–32701 | Not calculated | Not calculated | ||
UL16 | Tegument protein | 28183–29274 | − | 92.9 | 57.9 |
UL17 | DNA packaging tegument protein | 29306–31465 | − | 87.9 | 57.7 |
UL18 | Capsid triplex subunit 2; VP23 | 32805–33761 | − | 96.2 | 78.3 |
UL19 | Major capsid protein; VP5 | 33904–38049 | − | 95.9 | 82.8 |
UL20 | Envelope protein | 38218–38880 | − | 92.7 | 62.6 |
UL21 | Tegument protein | 39328–40893 | + | 91.2 | 59.9 |
UL22 | Envelope glycoprotein H | 40993–43563 | − | 89.9 | 48.8 |
UL23 | Thymidine kinase | 43733–44722 | − | 84.2 | 41.9 |
UL24 | Nuclear protein | 44802–45593 | + | 83.7 | 58.8 |
UL25 | DNA packaging tegument protein | 45792–47540 | + | 95.0 | 76.3 |
UL26 | Capsid maturation protease | 47619–49502 | + | 84.7 | 55.5 |
UL27 | Envelope glycoprotein B | 49833–52052 | − | 94.7 | 59.0 |
UL28 | DNA packaging terminase subunit 2 | 52477–54837 | − | 91.3 | 71.4 |
UL29 | Single-stranded DNA-binding protein; ICP8 | 54976–58566 | − | 95.9 | 81.1 |
UL30 | DNA polymerase catalytic subunit | 59282–62989 | + | 92.2 | 73.5 |
UL31 | Nuclear egress lamina protein | 62916–63848 | − | 95.8 | 74.0 |
UL32 | DNA packaging protein | 63841–65592 | − | 92.1 | 70.2 |
UL33 | DNA packaging protein | 65591–65980 | + | 94.6 | 65.6 |
UL34 | Nuclear egress membrane protein | 66042–66872 | + | 87.7 | 57.6 |
UL35 | Small capsid protein | 66957–67286 | + | 92.7 | 56.6 |
UL36 | Large tegument protein | 67381–75249 | − | 76.1 | 46.9 |
UL37 | Tegument protein | 76461–79718 | − | 93.5 | 62.0 |
UL38 | Capsid triplex subunit 1 | 80085–81473 | + | 83.3 | 59.6 |
UL39 | Ribonucleotide reductase subunit 1 | 81831–85625 | + | 82.5 | 52.9 |
UL40 | Ribonucleotide reductase subunit 2 | 85661–86668 | + | 94.9 | 73.8 |
UL41 | Tegument host shutoff protein | 86793–88286 | − | 94.6 | 64.5 |
UL42 | DNA polymerase processivity subunit | 88701–90164 | + | 74.7 | 46.1 |
UL43 | Envelope protein | 90326–91510 | + | 78.9 | 36.3 |
UL44 | Envelope glycoprotein C | 91687–93075 | + | 81.4 | 44.0 |
UL45 | Membrane protein | 93186–93698 | + | 86.5 | 44.8 |
UL46 | Tegument protein VP11/12 | 93778–96186 | − | 86.9 | 49.9 |
UL47 | Tegument protein VP13/14 | 96249–98378 | − | 87.7 | 55.8 |
UL48 | Transactivating tegument protein VP16 | 98738–100186 | − | 91.9 | 65.5 |
UL49 | Tegument protein VP22 | 100578–101447 | − | 77.2 | 39.4 |
UL49A | Envelope glycoprotein N | 101767–102012 | − | 81.5 | 30.8 |
UL50 | Deoxyuridine triphosphatase | 102025–103089 | + | 89.8 | 41.3 |
UL51 | Tegument protein | 103210–103899 | − | 90.4 | 59.6 |
UL52 | Helicase-primase primase subunit | 103975–107115 | + | 87.0 | 63.1 |
UL53 | Envelope glycoprotein K | 107085–108092 | + | 93.7 | 64.8 |
UL54 | Multifunctional expression regulator; ICP27 | 108732–110366 | + | 77.7 | 54.1 |
UL55 | Nuclear protein | 110705–111256 | + | 97.3 | 61.8 |
UL56 | Membrane protein | 111957–112835 | − | 67.5 | 26.8 |
RL2 | Ubiquitin E3 ligase; ICP0 | − | Not calculated | 17.6 | |
Exon 1 | 116672–117061 | Not calculated | Not calculated | ||
Exon 2 | 114829–115422 | Not calculated | Not calculated | ||
RL1 | ICP34.5 | 118066–118953 | − | 80.4 | 34.6 |
RS1 | ICP4 | 121128–124547 | − | 85.4 | 56.4 |
US1 | Regulatory protein ICP22 | 126048–127286 | + | 68.3 | 37.0 |
US2 | Virion protein | 127413–128315 | − | 89.3 | 59.2 |
US3 | Serine/threonine protein kinase | 128549–129946 | + | 90.3 | 58.6 |
US4 | Envelope glycoprotein G | 130039–132231 | + | 54.2 | 11.1 |
US5 | Envelope glycoprotein J | 132460–133098 | + | Not calculated | 14.7 |
US6 | Envelope glycoprotein D | 133385–134557 | + | 88.0 | 57.6 |
US7 | Envelope glycoprotein I | 134720–136102 | + | 60.8 | 35.6 |
US8 | Envelope glycoprotein E | 136322–137989 | + | 71.7 | 39.9 |
US8A | PtAHV1 US8A-like protein | 137931–138221 | + | 55.6 | 22.8 |
RS1 | ICP4 | 139854–143273 | + | 85.4 | 56.4 |
+ and −, forward and reverse directions, respectively.