Skip to main content
. 2020 Aug 31;94(18):e00673-20. doi: 10.1128/JVI.00673-20

TABLE 2.

Genes predicted in the PLAHV genome

Gene Product Positions Orientationa % amino acid sequence identity to:
PtAHV1 HSV-1
RL1 ICP34.5 1405–2292 + 80.4 34.6
RL2 Ubiquitin E3 ligase; ICP0 + Not calculated 17.6
Exon 1 3297–3686 Not calculated Not calculated
Exon 2 4936–5529 Not calculated Not calculated
UL1 Envelope glycoprotein L 7226–7933 + 74.6 36.6
UL2 Uracil-DNA glycosylase 8328–8990 + 89.1 46.4
UL3 Nuclear protein 9074–9742 + 82.9 53.8
UL4 Nuclear protein 9789–10421 89.7 44.4
UL5 Helicase-primase helicase subunit 10455–13076 95.1 78.4
UL6 Capsid portal protein 13075–15120 + 94.0 64.1
UL7 Tegument protein 15071–15958 + 92.9 61.1
UL8 Helicase-primase subunit 16077–18083 77.8 42.8
UL9 DNA replication origin-binding helicase 18436–20985 96.7 78.0
UL10 Envelope glycoprotein M 20942–22297 + 94.9 58.3
UL11 Myristylated tegument protein 22917–23174 88.2 44.8
UL12 DNase 23099–25069 80.4 50.4
UL13 Tegument serine/threonine protein kinase 25072–26619 96.7 66.2
UL14 Tegument protein 26379–26891 90.6 49.5
UL15 DNA packaging terminase subunit 1 + 97.3 82.7
Exon 1 27110–28135 Not calculated Not calculated
Exon 2 31526–32701 Not calculated Not calculated
UL16 Tegument protein 28183–29274 92.9 57.9
UL17 DNA packaging tegument protein 29306–31465 87.9 57.7
UL18 Capsid triplex subunit 2; VP23 32805–33761 96.2 78.3
UL19 Major capsid protein; VP5 33904–38049 95.9 82.8
UL20 Envelope protein 38218–38880 92.7 62.6
UL21 Tegument protein 39328–40893 + 91.2 59.9
UL22 Envelope glycoprotein H 40993–43563 89.9 48.8
UL23 Thymidine kinase 43733–44722 84.2 41.9
UL24 Nuclear protein 44802–45593 + 83.7 58.8
UL25 DNA packaging tegument protein 45792–47540 + 95.0 76.3
UL26 Capsid maturation protease 47619–49502 + 84.7 55.5
UL27 Envelope glycoprotein B 49833–52052 94.7 59.0
UL28 DNA packaging terminase subunit 2 52477–54837 91.3 71.4
UL29 Single-stranded DNA-binding protein; ICP8 54976–58566 95.9 81.1
UL30 DNA polymerase catalytic subunit 59282–62989 + 92.2 73.5
UL31 Nuclear egress lamina protein 62916–63848 95.8 74.0
UL32 DNA packaging protein 63841–65592 92.1 70.2
UL33 DNA packaging protein 65591–65980 + 94.6 65.6
UL34 Nuclear egress membrane protein 66042–66872 + 87.7 57.6
UL35 Small capsid protein 66957–67286 + 92.7 56.6
UL36 Large tegument protein 67381–75249 76.1 46.9
UL37 Tegument protein 76461–79718 93.5 62.0
UL38 Capsid triplex subunit 1 80085–81473 + 83.3 59.6
UL39 Ribonucleotide reductase subunit 1 81831–85625 + 82.5 52.9
UL40 Ribonucleotide reductase subunit 2 85661–86668 + 94.9 73.8
UL41 Tegument host shutoff protein 86793–88286 94.6 64.5
UL42 DNA polymerase processivity subunit 88701–90164 + 74.7 46.1
UL43 Envelope protein 90326–91510 + 78.9 36.3
UL44 Envelope glycoprotein C 91687–93075 + 81.4 44.0
UL45 Membrane protein 93186–93698 + 86.5 44.8
UL46 Tegument protein VP11/12 93778–96186 86.9 49.9
UL47 Tegument protein VP13/14 96249–98378 87.7 55.8
UL48 Transactivating tegument protein VP16 98738–100186 91.9 65.5
UL49 Tegument protein VP22 100578–101447 77.2 39.4
UL49A Envelope glycoprotein N 101767–102012 81.5 30.8
UL50 Deoxyuridine triphosphatase 102025–103089 + 89.8 41.3
UL51 Tegument protein 103210–103899 90.4 59.6
UL52 Helicase-primase primase subunit 103975–107115 + 87.0 63.1
UL53 Envelope glycoprotein K 107085–108092 + 93.7 64.8
UL54 Multifunctional expression regulator; ICP27 108732–110366 + 77.7 54.1
UL55 Nuclear protein 110705–111256 + 97.3 61.8
UL56 Membrane protein 111957–112835 67.5 26.8
RL2 Ubiquitin E3 ligase; ICP0 Not calculated 17.6
Exon 1 116672–117061 Not calculated Not calculated
Exon 2 114829–115422 Not calculated Not calculated
RL1 ICP34.5 118066–118953 80.4 34.6
RS1 ICP4 121128–124547 85.4 56.4
US1 Regulatory protein ICP22 126048–127286 + 68.3 37.0
US2 Virion protein 127413–128315 89.3 59.2
US3 Serine/threonine protein kinase 128549–129946 + 90.3 58.6
US4 Envelope glycoprotein G 130039–132231 + 54.2 11.1
US5 Envelope glycoprotein J 132460–133098 + Not calculated 14.7
US6 Envelope glycoprotein D 133385–134557 + 88.0 57.6
US7 Envelope glycoprotein I 134720–136102 + 60.8 35.6
US8 Envelope glycoprotein E 136322–137989 + 71.7 39.9
US8A PtAHV1 US8A-like protein 137931–138221 + 55.6 22.8
RS1 ICP4 139854–143273 + 85.4 56.4
a

+ and −, forward and reverse directions, respectively.

HHS Vulnerability Disclosure