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. 2020 Aug 4;9(8):634. doi: 10.3390/pathogens9080634

Table 1.

Quantitative histological measurements of alveolar echinococcosis lesions in liver tissues.

Histological Parameter Lesion Measurements; Mean ± SD
Median
(Min–Max)
p-Value b
Type I Type II Type III Type IV Type V a
Width of border zone (µm) 377.80 ± 64.53
375.99
302.87–487.18
391.83 ± 109.36
361.37
271.41–584.91
454.07 ± 127.49
416.34
286.74–672.44
334.27 ± 103.34
291.47
224.80–573.34
388.54 0.0621
Zone of epithelioid cells (µm) 120.84 ± 26.24
128.02
70.01-165.28
127.76 ± 32.73
116.51
79.74-188.09
115.37 ± 21.98
110.23
90.67-154.85
147.88 ± 77.78
126.20
47.22–340.68
106.33 0.5965
Zone of fibrosis (µm) 147.61 ± 35.27
153.27
87.71–195.12
147.52 ± 54.46
133.59
84.35–272.71
212.92 ± 113.66
169.03
101.90–461.28
102.74 ± 37.06
94.14
62.97–171.22
184.09 0.0089 **
Zone of lymphocytes (µm) 109.36 ± 29.91
107.62
77.37–186.93
116.55 ± 55.23
109.73
69.88–267.44
125.78 ± 32.36
117.76
82.10–174.93
83.65 ± 33.71
74.12
38.96–159.10
98.13 0.0297 *
Thickness of laminated layer fragments (µm) 24.67 ± 7.36
23.89
12.64–37.41
22.85 ± 9.36
24.07
8.86–41.86
46.68 ± 57.17
22.64
15.68–193.32
27.14 ± 12.06
27.95
11.83-46.95
22.72 0.9000
Distance between laminated layer and border zone (µm) 318.16 ± 266.48
264.80
28.00–926.92
464.26 ± 502.04
180.30
30.10–1266.50
756.60 ± 969.42
238.04
38.40–2479.60
2037.75 ± 968.43
1842.40
842.80–4533.80
120.62 0.0003 ***
Spems in necrotic area (relative area covered by mAbEm2G11-positive stained spems in a single observation field; magnification 100×) 0.51 ± 0.19
0.54
0.17–0.81
0.34 ± 0.24
0.23
0.07–0.68
0.38 ± 0.25
0.43
0.04–0.80
0.32 ± 0.20
0.31
0.01–0.66
- 0.2621

* p < 0.05; ** p < 0.01; *** p < 0.001. a Type V was excluded from the analysis due to the small number of lesions. b p-values were calculated only for types I–IV.