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. 2020 Aug 4;9(8):634. doi: 10.3390/pathogens9080634

Table 2.

Semi-quantitative histological measurements of alveolar echinococcosis lesions in liver tissues.

Histological Parameter Number of Lesions (Percent for Each Type) p-Value b
Type I Type II Type III Type IV Type V a
Localisation of laminated layer fragments Distributed throughout the necrotic area 11 (100.00) 11 (100.00) 10 (100.00) 1 (9.09) 2 (100.00) <0.0001 ***
Centralised alveolae 0 (0.00) 0 (0.00) 0 (0.00) 10 (90.01) 0 (0.00)
Number of necrotic areas per section Multiple necrotic areas 10 (90.91) 5 (45.45) 7 (70.00) 1 (9.09) 1 (50.00) 0.0010 **
Single necrotic area 1 (9.09) 6 (54.55) 3 (30.00) 10 (90.91) 1 (50.00)
Outer fibrotic rim (Zone 3b) No fibrosis 10 (90.91) 10 (90.91) 3 (30.00) 11 (100.00) 1 (50.00) 0.0002 ***
Fibrosis 1 (9.09) 1 (9.09) 7 (70.00) 0 (0.00) 1 (50.00)
Spems in necrotic area (scored 1–3) 1 (spems only attached to the laminated layer) 0 (0.00) 0 (0.00) 2 (20.00) 2 (18.18) 0 (0.00) no p-value calculated
2 (spems in entire necrotic area, but less abundant near the border) 6 (54.55) 7 (63.64) 3 (30.00) 6 (54.55) 0 (0.00)
3 (spems in entire necrotic area) 5 (45.45) 4 (36.36) 5 (50.00) 3 (27.27) 2 (100.00)
Spems in non-necrotic liver tissue No spems 2 (18.18) 5 (45.45) 1 (10.00) 7 (63.64) 0 (0.00) 0.0348 *
Spems 9 (81.82) 6 (54.55) 9 (90.00) 4 (36.36) 2 (100.00)

* p < 0.05; ** p < 0.01; *** p < 0.001. a Type V was excluded from the analysis due to the small n. b p-values were calculated only for types I–IV.