Table 7.
IC50 of G6PD inhibitory activity and names of compounds in Scheme 9.
| No. | IC50 (μM) | Names |
|---|---|---|
| 7.3.1 | 76.6 ± 0.1 (a) | 3,5-dibromo-4-hydroxybenzaldehyde [117] |
| 7.3.2 | 4.01 ± 0.3 (a), | 3,4-dibromo-5-(2-bromo-3,4-dihydroxy-6-(hydroxymethyl)benzyl)benzene-1,2-diol [117] |
| 7.3.3 | 0.85 ± 0.1 (a) | Bis(2,3-dibromo-4,5-dihydroxybenzyl)ether [117] |
| 7.3.4 | 321 ± 18 (a) | 3,4-dibromo-5-(butoxymethyl)benzene-1,2-diol [118] |
| 7.3.5 | 0.97 ± 0.1 (a) | Bis-(2,3,6-tribromo-4,5-dihydroxybenzyl methyl ether) [118] |
| 7.3.6 | 0.85 ± 0.1 (a) | 5,5’-(oxybis(methylene))bis(3,4-dibromobenzene-1,2-diol) [118] |
| 7.3.7 | 0.47 ± 0.03 (a) | 5,5’-methylenebis(3,4-dibromobenzene-1,2-diol) [118] |
| 7.3.8 | 0.53 ± 0.18 (a) | 3,4-dibromo-5-(2-bromo-3,4-dihydroxy-6-(methoxymethyl)benzyl)benzene-1,2-diol [118] |
Notes: a, Leuconostoc mesenteroides G6PD; b, Saccharomyces cerevisiae G6PD.