Table 2.

Second-generation aza-GHRP-6 analogues from alanine scanning.

Compound	GHS-R1a EC50 (M)	CD36 EC50 (M)
[Ala1, azaPhe2]GHRP-6 (10)	» 10−5	4.27 × 10−5
[Ala1, azaTyr2]GHRP-6 (11)	» 10−5	3.69 × 10−5
[Ala1, azaLeu3]GHRP-6 (12)	1.2×10−5	6.66 × 10−6
[azaLeu3, Ala4]GHRP-6 (13)	» 10−5	2.59 × 10−5
[azaLeu3, d-Ala5]GHRP-6 (14)	» 10−5	9.48 × 10−6
[Ala1, azaPhe4]GHRP-6 (15)	» 10−5	7.58 × 10−6