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. 2020 Aug 7;18(8):415. doi: 10.3390/md18080415

Figure 3.

Figure 3

Effects of astaxanthin on apoptosis in DU145 cells. The experiments were divided into five groups. CK was the blank control group. The astaxanthin group was pretreated with astaxanthin for 24 h. The si-STAT3 group was transfected with siRNA-STAT3 for 48 h, and the siRNA-NC group was the blank control to si-STAT3. The astaxanthin+si-STAT3 group was transfected with a si-STAT3 plasmid for 48 h and then treated with astaxanthin for 24 h. (A) The progression of the apoptotic cells and the respective phase were analyzed with Annexin V-FITC assay. (B) The apoptosis rate was analyzed. The results show that both astaxanthin and si-STAT3 promote the apoptosis of DU145 cells, while the effect of astaxanthin combined with si-STAT3 is enhanced. Data are presented as the average of three experiments (±SD), ** p < 0.01 and *** p < 0.001.