Table 3.
Parameter 1 | Parameter 2 | p-Value, ρ-Value | Cases |
---|---|---|---|
Tumor Infiltrating Lymphoc Ytes | |||
Average stromal TILs in CT | Max. stromal TILs in CT | p = 0.000; ρ = 0.731 | n = 107 |
Average stromal TILs at IM | p = 0.000; ρ = 0.563 | n = 102 | |
Max. stromal TILs at IM | p = 0.000; ρ = 0.420 | n = 102 | |
Max. stromal TILs in CT | Max. stromal TILs at IM | p = 0.000; ρ = 0.546 | n = 102 |
Average stromal TILs at IM | Max. stromal TILs at IM | p = 0.000; ρ = 0.698 | n = 102 |
Max. stromal TILs in CT | p = 0.000; ρ = 0.436 | n = 102 | |
Average IT TILs at IM | p = 0.038; ρ=0.206 | n = 102 | |
Average IT TILs in CT | Max. IT TILs in CT | p = 0.000; ρ = 0.831 | n = 107 |
Max. IT TILs at IM | p = 0.000; ρ = 0.734 | n = 102 | |
Average IT TILs at IM | p = 0.000; ρ = 0.739 | n = 102 | |
Max. IT TILs in CT | Max. IT TILs at IM | p = 0.000; ρ = 0.936 | n = 102 |
Average IT TILs at IM | p = 0.000; ρ = 0.899 | n = 102 | |
Histological Features | |||
Degree of invasion | Degree of necrosis | p = 0.000; ρ = 0.352 | n = 103 |
Grading score | Degree of invasion | p = 0.000; ρ = 0.364 | n = 103 |
Degree of necrosis | p = 0.003; ρ = 0.284 | n = 107 | |
Tumor grade | Degree of invasion | p = 0.002; ρ = 0.299 | n = 103 |
Degree of necrosis | p = 0.029; ρ = 0.211 | n = 107 | |
Tumor Infiltrating Lymphocytes and Histological Features | |||
Max. stromal TILs in CT | Mitotic count | p = 0.042; ρ = −0.197 | n = 107 |
Grading score | p = 0.035; ρ = −0.204 | n = 107 | |
Tumor grade | p = 0.027; ρ = −0.213 | n = 107 | |
Immunohistochemical and Histological Features | |||
IRS estrogen receptor | IRS progesterone receptor | p = 0.000; ρ = 0.606 | n = 107 |
Mitotic count | p = 0.012; ρ = −0.243 | n = 107 | |
IRS progesterone receptor | Mitotic count | p = 0.008; ρ = −0.255 | n = 107 |
Degree of necrosis | p = 0.009; ρ = −0.250 | n = 107 | |
Calponin pos. tumor cells | Mitotic count | p = 0.035; ρ = −0.204 | n = 107 |
Calponin Positive Tumor Cells and Tumor Infiltrating lymphocytes | |||
Calponin positive tumor cells | Max. stromal TILs in CT | p = 0.012; ρ = 0.241 | n = 107 |
Average stromal TILs in CT | p = 0.026; ρ = 0.215 | n = 107 | |
Average stromal TILs at IM | p = 0.026; ρ = 0.220 | n = 107 |
CT = central tumor; IM = invasive margin; IRS = immunoreactive score; IT = intra-tumoral; Max. = maximal; Min. = minimal; TILs = tumor infiltrating lymphocytes; n = numbers of evaluated cases.