Table 1.

Model-based estimates for the example: Mean values and standard deviations of the initial values and increments for anaerobic bacteria and Rothia spp. with 95% CI. ${\widehat{\sigma }}_{\mathsf{\Delta }}$ indicates the common SD for the increments of phase 2–5. ${\eta }_i$ coherence of the individual changes with the mean change per phase.

Estimate	Anaerobic bacteria		Rothia spp.
	Estimate	95% CI	Estimate	95% CI
Initial Values
${\widehat{\mu }}_{\alpha }$	6.644	[5.995, 7.294]	5.833	[5.355, 6.312]
${\widehat{\sigma }}_{\alpha }$	1.000	[ 0.621, 1.611]	0.435	[0.212, 0.888]
Increments
${\widehat{\mu }}_{{\mathsf{\Delta }}_2}$	−0.319	[−0.840, 0.201]	0.639	[0.042, 1.235]
${\widehat{\mu }}_{{\mathsf{\Delta }}_3}$	0.129	[−0.392, 0.649]	0.506	[−0.091, 1.102]
${\widehat{\mu }}_{{\mathsf{\Delta }}_4}$	−0.269	[−0.790, 0.251]	−0.132	[−0.729, 0.464]
${\widehat{\mu }}_{{\mathsf{\Delta }}_5}$	−0.741	[−1.262, −0.221]	−0.377	[−0.973, 0.219]
${\widehat{\sigma }}_{{\mathsf{\Delta }}_2}$	0.209	[0.004, 10.142]	0.000	[0, ∞ ]
${\widehat{\sigma }}_{{\mathsf{\Delta }}_3}$	0.000	[0.000, 0.404]	0.000	[0, ∞ ]
${\widehat{\sigma }}_{{\mathsf{\Delta }}_4}$	0.681	[0.321, 1.448]	0.605	[0, ∞ ]
${\widehat{\sigma }}_{{\mathsf{\Delta }}_5}$	0.720	[0.354, 1.463]	0.556	[0, ∞ ]
${\widehat{\sigma }}_{\mathsf{\Delta }}$	0.542	[0.297, 0.990]	0.290	[0.041, 2.018]
Coherence
${\eta }_2$	72.3		98.6
${\eta }_3$	59.5		96.1
${\eta }_4$	69.1		67.3
${\eta }_5$	91.5		90.5