Table 4.
Statistically significant correlations between imaging biomarkers and functional parameters with |r| > 0.4.
| Handgrip (kg) | MeanISOMED (kg) | Max ISOMED (kg) | SPPB (Points) | MILP (kg) | |
|---|---|---|---|---|---|
| Muscle hydration ADC (10−3 mm2/s) | −0.28 | −0.36 | −0.23 | −0.28 | −0.36 |
| Muscle hydration D (10−3 mm2/s) | −0.28 | −0.42 | −0.45 | 0.02 | −0.27 |
| Muscle hydration T2* (ms) | − 0.27 | −0.02 | 0.03 | −0.23 | −0.51 * |
| Muscle microscopic fat (PDFF, no units) | −0.51 * | −0.11 | −0.21 | −0.27 | 0.10 |
| Macroscopic fatty infiltration (no units) | −0.10 | −0.15 | −0.20 | −0.60 ** | 0.01 |
| Muscle/fat ratio (no units) | −0.18 | −0.57 * | −0.46 * | 0.11 | −0.18 |
| Muscle/bone ratio (no units) | 0.22 | −0.42 | −0.42 * | 0.39 * | −0.28 |
| Absolute muscle volume (L) | 0.50 ** | 0.25 | 0.26 | 0.47 ** | 0.10 |
Abbreviations: ADC (apparent diffusion coefficient), D (diffusion coefficient), T2 (transversal relaxation time), PDFF (proton density fat fraction), Mean ISOMED (mean isometric knee extension), Max ISOMED (maximum isometric knee extension), SPPB (short physical performance battery), MILP (maximum isotonic leg press). Significant * < 0.05; ** < 0.01.