Table 1.
Frequency of CYP11B1, CYP11B2, CYP17A1 and StAR immunostaining positivity in the different adrenocortical tumors.
| Adrenocortical Tumors | Steroidogenic Proteins | Negative | Positive |
|---|---|---|---|
| ACC (n = 14) | CYP11B1 | 5 (35.7%) | 9 (64.3%) |
| CYP11B2 | 11 (78.6%) | 3 (21.4%) | |
| CYP17A1 | 0 (0.00%) | 14 (100.0%) | |
| StAR | 0 (0.00%) | 14 (100.0%) | |
| ACAc (n = 11) | CYP11B1 | 0 (0.00%) | 11 (100.0%) |
| CYP11B2 | 5 (45.5%) | 6 (54.5%) | |
| CYP17A1 | 0 (0.00%) | 11 (100.0%) | |
| StAR | 0 (0.00%) | 11 (100.0%) | |
| ACAn (n = 15) | CYP11B1 | 2 (13.3%) | 13 (86.7%) |
| CYP11B2 | 7 (46.7%) | 8 (53.3%) | |
| CYP17A1 | 1 (6.7%) | 14 (93.3%) | |
| StAR | 0 (0.00%) | 15 (100.0%) |
ACC—Adrenocortical carcinomas, ACAc—Adrenocortical adenomas with Cushing’s syndrome, ACAn—non-functioning adrenocortical adenomas, CYP11B1—11β-hydroxylase, CYP11B2—Aldosterone synthase, CYP17A1—17α-hydroxylase, and StAR—Steroidogenic acute regulatory protein.