Table 2.
First line | Characteristics | No. | Events | HR (95%CI) | Median PFS (95%CI) | p-Value |
PR | ||||||
Low (<20%) | 17 | 11 | 2.07 (0.87–4.9) | 7.0 (3.0, NA) | 0.099 | |
High (≥20%) | 30 | 10 | 1.00 | 15.0 (12.0, NA) | ||
Ki67 | ||||||
Low (<20%) | 31 | 11 | 1.00 | 15.0 (12.0, NA) | 0.233 | |
High (≥20%) | 16 | 10 | 1.69 (0.71–3.99) | 8.5 (5.0, NA) | ||
Luminal | ||||||
A | 22 | 5 | 1.00 | 14.0 (14.0, NA) | 0.053 | |
B | 25 | 16 | 2.72 (0.99–7.48) | 7.0 (5.0, NA) | ||
PR (continuous) | 0.99 (0.98–1.01) | - | 0.293 | |||
Ki67 (continuous) | 1.04 (1.01–1.08) | - | 0.008 | |||
Second line | PR | |||||
Low (<20%) | 9 | 5 | 1.00 | 9.0 (7.0, NA) | 0.335 | |
High (≥20%) | 11 | 6 | 1.88 (0.2, 6.82) | 11.0 (10.0, NA) | ||
Ki67 | ||||||
Low (<20%) | 6 | 3 | 1.50 (0.37, 6.14) | 9.0 (5.0, NA) | 0.570 | |
High (≥20%) | 13 | 8 | 1.00 | 11.0 (7.0, NA) | ||
Luminal | ||||||
A | 2 | 1 | 1.44 (0.17, 12.06) | 9.0 (NA, NA) | 0.735 | |
B | 17 | 10 | 1.00 | 11.0 (7.0, NA) | ||
PR (continuous) | 1.01 (0.99, 1.02) | - | 0.461 | |||
Ki67 (continuous) | 1.03 (0.97, 1.10) | - | 0.346 |
NA, not applicable.