Table 2.
The role of key endocrines that are involved in adipose metabolism 1.
| Endocrines 2 | β-Oxidation | Endocrines 3 | β-Oxidation |
|---|---|---|---|
| PPARα | + | SERBP | +− |
| AMPK | + | PPARγ | +− |
| CPT-1 | + | C/EBPα | +− |
| ACC1 | − | FAS | +− |
| Malonyl-CoA | − | ATGL | +− |
1 “+”: accelerates β-oxidation; “−”: suppresses β-oxidation; “+−”: indirectly promotes β-oxidation (by increasing fatty acids amount). 2 PPARα: peroxisome proliferator-activated receptor α; AMPK: AMP-activated protein kinase; CPT-1: carnitine palmitoyltransferase-1; ACC1: acetyl-CoA carboxylase. 3 SERBP: sterol regulatory element-binding proteins; PPARγ: peroxisome proliferator-activated receptor γ; C/EBP-α: CCAAT/enhancer-binding protein alpha; FAS: fatty acid synthase; ATGL: adipose triglyceride lipase.