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. 2020 Aug 4;9(8):480. doi: 10.3390/antibiotics9080480

Table 1.

Plant-derived substances and their action against different microbes.

Plant Name Plant Derivatives Bacterial sp. * MIC Value References
Anogeissusa cuminata terpenoids, flavonoids, saponins, tannins, alkaloids S. aureus 0.29 mg/mL [83]
A. baumannii 1.51 mg/mL
C. freundii 3.41 mg/mL
E. coli 3.41 mg/mL
K. oxytoca 1.51 mg/mL
K. pneumoniae 0.67 mg/mL
P. aeruginosa 0.67 mg/mL
Azadirachta indica β-sitosterol, flavonoids S. aureus 3.41 mg/mL [83]
[84]
A. baumannii 4.27 mg/mL
C. freundii 3.41 mg/mL
E. coli 4.27 mg/mL
K. oxytoca 9.63 mg/mL
K. pneumoniae 4.27 mg/mL
P. aeruginosa
H. pylori
9.63 mg/mL
128 µg/mL
Bauhinia variegata terpenoids, flavonoids, tannins, saponins, glucoside, S. aureus 3.41 mg/mL [83]
A. baumannii 9.63 mg/mL
C. freundii 9.63 mg/mL
E. coli 4.27 mg/mL
K. oxytoca 9.63 mg/mL
K. pneumoniae 4.27 mg/mL
P. aeruginosa 3.41 mg/mL
Boerhaavia diffusa β-sitosterol, flavonoids S. aureus 4.27 mg/mL [83]
A. baumannii 9.63 mg/mL
C. freundii 9.63 mg/mL
E. coli NA
K. oxytoca 9.63 mg/mL
K. pneumoniae 9.63 mg/mL
P. aeruginosa 9.63 mg/mL
Punica granatum flavonoids, ellagitannin, punicalagin, ellagic acid S. aureus 0.29 mg/mL [83]
A. baumannii 3.41 mg/mL
C. freundii 0.67 mg/mL
E. coli 0.67 mg/mL
K. oxytoca 3.41 mg/mL
K. pneumoniae 3.41 mg/mL
P. aeruginosa 0.67 mg/mL
Soymida febrifuga methyl angolensate, luteolin 7-O-glucoside, flavonoid, sitosterol, myricetin S. aureus 067 mg/mL [83]
A. baumannii 1.51 mg/mL
C. freundii 3.41 mg/mL
E. coli 4.27 mg/mL
K. oxytoca 3.41 mg/mL
K. pneumoniae 3.41 mg/mL
P. aeruginosa 4.27 mg/mL
Terminalia chebula flavonoids and flavins, terpenoids, steroids, alkaloids, tannins and their derivatives, glycosides S. aureus 1.51 mg/mL [83]
A. baumannii 9.63 mg/mL
C. freundii NA
E. coli 9.63 mg/mL
K. oxytoca 9.63 mg/mL
K. pneumoniae 9.63 mg/mL
P. aeruginosa 9.63 mg/mL
Tinospora cordifolia alkaloids terpenoids, lactones, glycosides, steroids, phenolics S. aureus 4.27 mg/mL [83]
A. baumannii NA
C. freundii 9.63 mg/mL
E. coli 4.27 mg/mL
K. oxytoca 9.63 mg/mL
K. pneumoniae 9.63 mg/mL
P. aeruginosa 4.27 mg/mL
Tribulus terrestris flavonoids, flavonol glycosides, steroidal saponins and alkaloids S. aureus 3.41 mg/mL [83]
A. baumannii 9.63 mg/mL
C. freundii 9.63 mg/mL
E. coli 4.27 mg/mL
K. oxytoca 4.27 mg/mL
K. pneumoniae 9.63 mg/mL
P. aeruginosa 3.41 mg/mL
Petroselinum crispum EO (Essential oil) phenolic, flavonoids, coumarins B. cereus 22.68 µL/mL [85]
S. aureus 10.80 µL/mL
P. aeruginosa 47.62 µL/mL
E. coli 10.80 µL/mL
S. typhimurium 47.62 µL/mL
Levisticum officinale EO terpenoids, n-butylidene phthalide n-butyl-phthalide, sedanonic anhydride, d-terpineol, l, l phenolic, B. cereus 47.62 µL/mL [85]
S. aureus 2.45 µL/mL
P. aeruginosa 22.68 µL/mL
E. coli 10.80 µL/mL
S. typhimurium 47.62 µL/mL
Occimomum basilicum EO rosmarinic acid, phenol and terpenoid B. cereus 10.80 µL/mL [85]
S. aureus 2.45 µL/mL
P. aeruginosa 22.68 µL/mL
E. coli 10.80 µL/mL
S. typhimurium 22.68 µL/mL
Thymus vulgare EO p-cymene, γ-terpinene, thymol B. cereus 0.56 µL/mL [85]
S. aureus 0.06 µL/mL
P. aeruginosa 0.56 µL/mL
E. coli 0.27 µL/mL
S. typhimurium 0.56 µL/mL
Cannabis sativa L., EO phenol, flavonoid S. aureus 8 mg/mL [86]
Acrosta phylosuvaursi ellagic and gallic acid tannins, flavonoids, phenol S. aureus 90 µg/mL [87]
Coptis chinensis isoquinoline, alkaloids 121 µg/mL
Eucalyptus globulus 1,8-cineole, α-pinene, p-cymene 118 µg/mL
Larreatri dentata alkaloids, lignans, flavonoid, terpenoids 60 µg/mL
Alpinia galanga α-pinene, myrcene, limonene Mycobacterium smegmatis
mc2 155
3.12–25 mg/L [88]
Ammannia spp. dioxyflavanol, quercetin and kaempferol E. coli 125 µg/mL [89]
Berberis vulgaris isoquinoline, alkaloids, P. aeruginosa 250–1000 µg/mL [90]
Acer saccharum flavonoids, tannins E. coli 5 and 10 mg/mL [91]
P. aeruginosa
P. mirabilis
Catharanthus roseus limonene, terpenoid P. aeruginosa 25 mg/L [92]
Holarrhena antidysenterica triterpenoids, sitosterol, phytosterol P. aeruginosa 20 mg/L [93]
Cuminum cyminum alkaloid, phenols, flavonoid, glycoside, saponin, tannin and steroid S. aureus 5 mg/mL [94]
Salvia fruticosa flavonoids, phenolics and rosemarinic acid S. epidermidis 5 µl/mL [95]
Chenopodium Ambrosioides α-terpinene, ascaridole S. aureus 170.6 µl/mL [96]
Terminalia chebola ellagic acid, gallic acid E. coli 12.1–97.5 µg/mL [97]
Persea lingue flavonoids, S. aureus 1.56 mg/L [98]
Ipomoea muricata ipomine, ipalbine, ipalbidine and ipalbinium E. coli 10 µg/mL [99]
Hypericum olympicum essential oils, α-pinene, β-ocimene, β-caryophyllene, germacrene-D S. aureus 50 µM [100]
Alkanna orientalis β-eudesmol, α-eudesmol and γ-eudesmol S. aureus 100 µM [101]
Eucalyptus tereticornis saponins, tannins, steroids flavonoids, cardiac glycosides E. coli 25 and 50 µg/mL
[89]
Salvia officinalis phenols, terpenoids E. cloacae,
E. coli,
S. typhimurium,
P. aeruginosa,
B. cereus
0.01 mg/mL,
0.045 mg/mL,
0.045 mg/mL,
0.045 mg/mL,
0.09 mg/mL
[102]

* MIC corresponds to effect observed for the plant extract against given bacterial isolates.