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. 2020 Aug 18;10(8):604. doi: 10.3390/diagnostics10080604

Table 2.

Characteristics of included studies.

Author Population Sample (Men/Women) Mean Age (Years) Outcome Results Summary
Barbero et al. [10] Neck Pain
Low Back Pain
56 (15/41)
51 (20/31)
50.3 (15.0)
48.5 (14.1)
Pain Extent
Clinical outcomes: BMI, age, pain duration, pain (VAS, 0–100), function (NDI, or RMDQ)
Psychological outcomes: K-10, MoCa
Significant correlations were observed between pain extent and pain
intensity in both conditions, between pain extent and disability in neck pain
Lluch-Girbés et al. [20] Knee Osteoarthritis 53 (19/34) 70.2 (7.4) Pain Extent
Clinical outcomes: Pain (NPRS, 0–10), function (WOMAC)
Psychological outcomes: PCS, PVAQ, CPAQ, TSK
Psycho-physical outcomes: PPTs, CPM, CSI, PD-Q
Significant positive correlations between pain extent with pain and stiffness subscales of WOMAC and CSI score were found.
Significant negative correlations between pain extent and PPTs were found
Falla et al. [21] Whiplash-associated disorders 205 (133/72) 40.1 (11.4) Pain Extent
Clinical outcomes: Pain (VAS, 0–100), function (NDI, 0–100), PDI, EQ-5D
Psychological outcomes: TSK, PCS, HADS-A, HADS-D, SES
Others: Effort-Reward Imbalance Scale
Pain extent was influenced by sex, insurance status and worse financial situation.
Positive significant associations between pain extent with NDI, HADS-D and PDI were found.
A negative significant association between pain extent and SES was found
Palacios-Ceña et al. [22] Chronic Tension-Type Headache 99 (27/72) 47 (44–50) Pain Extent
Clinical outcomes: Age, headache intensity, duration and frequency, HDI-E, HDI-P
Psychological outcomes: HADS-A, HADS-D, STAI-T, STAI-S.
Psycho-physical outcomes: PPTs
Significant positive associations were found between pain extent with age and the burden of the headache (HDI-E and HDI-P)
Barbero et al. [23] Fibromyalgia 30 (0/30) 52 (12) Median Pain Extent
Clinical outcomes: Age, pain duration, pain (NPRS, 0–10), function (FIQ), tender point count
Psycho-physical outcomes: PPTs, HPTs, CPTs
Significant negative correlations were observed between pain extent with age and pain duration
A significant positive association between pain extent and worst level of pain was found
Cruder et al. [24] Musicians 158 (68/90) 22.4 (3.6) Pain extent
Clinical outcomes: BMI, practicing (hours), pain intensity (1–5), function (QD Score, and QD score optional module)
Significant positive correlations between pain extent with pain intensity, QD and QD optional module were found
Fernández-de-las-Peñas et al. [25] Episodic Migraine 72 (0/72) 42 (10.22) Pain extent
Clinical outcomes: Age, migraine intensity, duration and frequency
Psychological outcomes: HADS-A, HADS-D, STAI-T, STAI-S.
Psycho-physical outcomes: PPTs
No significant associations between pain extent with any clinical, psychological or psycho-physical variables were observed
Fernández-de-las-Peñas et al. [26] Carpal Tunnel Syndrome 140 (0/140) 47 (13.5) median Pain extent
Clinical outcomes: Age, pain duration, pain (NPRS, 0–10), function (BCTQ, 0–5)
Psycho-physical outcomes: PPTs, HPTs, CPTs
A significative positive correlation between pain extent and CPT over carpal tunnel was observed
Ris et al. [29] Neck pain
Traumatic Nek Pain
Non-traumatic Neck Pain
200 (75/125)
120
80
43.5 (11.4)
47.6 (11.4)
Pain Extent
Clinical outcomes: Function (NDI), quality of life (SF36)
Psychological outcomes: BDI-II, TSK
Others: ROM, CCFT
Significative positive correlations between pain extent with NDI (all groups), BDI-II (all groups) and TSK (neck pain and nontraumatic pain groups) were seen
Significative negative correlations between pain extent and muscle function (CCFT and CE) in neck pain and nontraumatic pain groups) were observed
Abichandani et al. [27] Chronic Neck Pain 20 (0/20) 26 (2–32) Median Pain Extent
Recognition of pain drawing
Clinical outcomes: age, pain duration, pain (NPRS, 0–10), NDI
Psychological outcomes: PCS, DASS-42, MSPQ
A significative negative correlation was observed between recognition of pain drawing and MSPQ
Willet et al. [28] Hip Osteoarthritis 30 (15/15) 61 (55.25–64) median Pain extent
Clinical outcomes: Age, function (Oxford Hip Score), pain (WPI), symptoms (FMS-SSS), PD-Q
Psychological outcomes: DASS, TSK, PCS, CPAQ
Psycho-physical outcomes: PTTs, CPTs, HPTs
Paint extent demonstrated significant association with WPI and PD-Q
Pain extent was also associated with lower PPTs in the lower extremity, higher CPTs at the greater trochanter, reduced HPTs at the greater trochanter and reduced WDTs over the thenar eminence

BMI: Body Mass Index; BCTQ: Boston Carpal Tunnel Questionnaire; BDI-II Beck Depression Inventory; CCFT: Cranio-cervical flexion test; CE: Cervical Extension; CPAQ: Chronic Pain Acceptance Questionnaire; CPM: Conditioned Pain Modulation; CPT: Cold Pain Threshold; CSI: Central Sensitization Inventory; DASS-42: Depression Anxiety and Stress Scale; DASS: Depression, Anxiety, Stress 21 Scale; FIQ: Fibromyalgia Impact Questionnaire; FMS-SSS: Fibromyalgia Symptom Scale; HADS-A: Hospital Anxiety and Depression Scale (Anxiety subscale); HADS-D: Hospital Anxiety and Depression Scale (Depression subscale); HPT: Heat Pain Threshold; K-10: Kessler Psychological Distress Scale; MoCa: Montreal Cognitive Assessment; MSPA: Modified Somatic Perceptions Questionnaire; NDI: Neck Disability Index; NPRS: Numeric Pain Rating Scale; PCS: Pain Catastrophizing; PDI: Pain Disability Index; PD-Q: Pain DETECT questionnaire; PPT: Pressure Pain Threshold; PVAQ: Pain Vigilance and Awareness; QD: Quick DASH; RMDQ: Roland and Morris Disability Questionnaire; ROM: Range of motion; SES: Self-Efficacy Scale; SF-36-MCS: Short-Form 36, Standardized Mental Component Summary Score; SF-36-PCS: Short-Form 36, Standardized Physical Component Summary Score; TS: Temporal summation; TSK-11: 11-item Tampa Scale of Kinesiophobia; VAS: Visual Analogue Scale WOMAC: Western Ontario and McMaster Universities Arthritis Index; WPI: Widespread Pain Index.