Table 3.
Significantly enriched biological processes involved in cell growth, development and lysine transport.
| Term ID | Description | Genes | Frequency (%) | Uniqueness |
|---|---|---|---|---|
| GO:0016049 | Cell growth | ALCAM, EXFABP, ID2, LLPH, SEMA5A, SEMA5B, SHH, TTR, ULK1 | 1.71 | 0.85 |
| GO:0022610 | Biological adhesion | M2, TENM3, TGFBI, THY1, TINAG, TINAGL1, TNFSF8, UBASH3B, VCL, VWA2 | 5.68 | 0.99 |
| GO:0032502 | Developmental process | SAP, PTK2, PTK7, PTN, PUM1, PXN, PYGO1, RAB10, RAB18, RAB3A, RAB8A, RAC3 | 21.32 | 1 |
| GO:0040007 | Growth | FGF1, GAP43, ID2, LARGE1, LLPH, PCK1, PSAP, PTK7, SEMA5A, SEMA5B, SHH, TEC, TTR, ULK1 | 3.21 | 0.99 |
| GO:0007154 | Cell communication | RNF152, RPTOR, RRAGC, SESN1, SESN2, SESN3, SIK2, SLC12A4, SLC12A7, STK11, WDR45B, WIPI2 | 27.90 | 0.98 |
| GO:0017144 | Drug metabolic process | CYP1A1, CYP1A2 | 0.05 | 0.97 |
| GO:0008283 | Drug Cell proliferation | ACE, ACVR2A, ACVR2B, BMP4, BMPR1A, CD180, CD40LG, ENTPD5, EXFABP, ID2, TGFB2, TOP2A, TWIST1, USP28, WNT2B, ASCC3 | 6.48 | 0.96 |
| GO:0043567 | Regulation of insulin-like growth factor receptor signaling pathway | IGFBP1, IGFBP2, IGFBP3, IGFBP4, IGFBP5 | 0.07 | 0.88 |
| GO:0008219 | Cell death | ATCAY, BNIP2, BRINP1, CASP10, CASP18, CASP2, CASP3, CASP7, CASP8, CASP9, STK4, TGFB2, TGFBR2, TNFRSF21, WNT1, XKR4, XKR9 | 6.39 | 0.9 |
| GO:0006950 | Response to stress | RPS27A, RPS3, RPTOR, RRAGC, SAMHD1, SELENOK, SEM1, SERP1, SESN1, SESN2, SESN3, SFR1, SGMS1 | 11.91 | 0.92 |
| GO:0006869 | Lipid transport | SLC43A2, SLC6A9, SLC7A1, SLC7A2, SLC7A3, SLC7A5, SLC7A9 | 1.42 | 0.87 |
| GO:0006629 | Lipid metabolic process | ACAT1, ACAT2, ACER3, ORMDL2, ORMDL3, OXSM, PCK1, PDCD2 | 5.34 | 0.88 |
| GO:0009267 | Cellular response to starvation | ATG7, BECN1, BMT2, EIF2S1, GABARAPL1 | 0.46 | 0.85 |
| GO:0044248 | Cellular catabolic process | ADH5, ADRM1, AFMID, AGL, AGO3, AGO4 | 5.96 | 0.93 |
| GO:0071398 | Cellular response to fatty acid | EXFABP, PTGER2 | 0.13 | 0.87 |
| GO:0048468 | Cell development | BMPR1A, CITED2, EXFABP, GDF11, HS6ST1, ID2, INHBA | 7.41 | 0.77 |
| GO:0055088 | Lipid homeostasis | ABCG1, ACOX1, ACOX2, EXFABP, LIPG, LPL, MTTP, ORMDL1, ORMDL2, ORMDL3, PLA2G12B, PNPLA2 | 0.41 | 0.91 |
| GO:0050801 | Ion homeostasis | ANXA5, ANXA6, ANXA7, ATOX1, ATP12A, SLC24A3, SLC30A9, SLC31A1, SLC35G1, SLC9A2, SLC9A7, SLC9A8, SLC9A9 | 2.62 | 0.89 |
| GO:0019477 | Lysine catabolic process | AASS | 1.35 | 0.91 |
| GO:0019878 | Lysine biosynthetic process via Aminoadipic acid | AASDHPPT, AASS | 7.50 | 0.9 |