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. 2020 Aug 17;21(16):5901. doi: 10.3390/ijms21165901

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Effects of the β-catenin-T-cell factors/lymphoid enhancer–binding factor (TCF/LEF) pathway inhibitors on cell viability of gastric cancer cells (AGS). (A) Representative morphology of AGS cells cultured for 96 h in the presence of 2,4-DAQ. Scale bar: 100 μm; (B) calculated IC50 growth inhibition values of 2,4-DAQ in three gastric cancer cell lines and immortalized human epithelial cells (GES-1); (C) dose- and time-dependent inhibition effect of 2,4-DAQ on three gastric cancer cell lines and GES-1 was evaluated by CCK-8 assay.