Table 1.
Laboratory indicators and behavior of fast metabolism (FM) and slow metabolism (SM) rats.
| FM (n = 42) | SM (n = 20) | |||
|---|---|---|---|---|
| Unstressed (n = 22) |
Stressed (n = 20) |
Unstressed (n = 8) |
Stressed (n = 12) |
|
| Time in open arms, s | 154.2 ± 24.6 | 258.5 ± 19.6 *** | 78.5 ± 16.6 # | 100.2 ± 21.4 ### |
| Time in closed arms, s | 445.8 ± 24.6 | 341.5 ± 19.6 *** | 521.5 ± 16.6 # | 499.8 ± 21.4 ### |
| Entries into open arms | 6.3 ± 0.6 | 8.7 ± 0.4 ** | 4.2 ± 0.5 # | 5.2 ± 0.6 ### |
| Entries into closed arms | 7.8 ± 0.8 | 10.6 ± 0.5 ** | 5.4 ± 0.6 # | 10.0 ± 0.9 ** |
| Anxiety index | 0.65 ± 0.02 | 0.56 ± 0.02 ** | 0.71 ± 0.02 # | 0.74 ± 0.02 ### |
| Grooming | 2.91 ± 0.55 | 2.63 ± 0.47 | 1.0 ± 0.3 | 2.5 ± 0.42 |
| Cort, nM/l | 197.4 ± 18.6 | 135.0 ± 13.1 * | 270.4 ± 37.1 # | 154.3 ± 25.3 ** |
| 11Dehydro Cort, nM/l | 1.3 ± 0.2 | 3.6 ± 0.8 | 5.5 ± 1.6 ### | 6.5 ± 1.9 |
| 6βCort in liver, nM/g | 0.28 ± 0.01 | 0.25 ± 0.02 | 0.14 ± 0.04 ## | 0.24 ± 0.04 * |
| 6βCort in blood, nM/l | 0.39 ± 0.05 | 0.65 ± 0.1 ** | 0.45 ± 0.04 | 0.52 ± 0.03 |
| 11βHSD-2, nmol min–1 g–1 | 9.73 ± 0.46 | 10.07 ± 0.94 | 13.45 ± 0.67 ## | 11.26 ± 0.96 |
Values are means ± SE. * Significantly different from unstressed rats; * p < 0.05; ** p < 0.01; *** p < 0.001. # Significantly different from fast metabolizers; # p < 0.05; ## p < 0.01; ### p < 0.001.