5 × STS	Five-time sit-to-stand
ADL	Activities of daily living
BIOSPHERE	BIOmarkers associated with Sarcopenia and PHysical frailty in EldeRly pErsons
CRP	C-reactive protein
CT	Computed tomography
DAMPs	Damage-associated molecular patterns
DXA	Dual energy x-ray absorptiometry
HSP72	HSP72, heat shock protein 72
IHG	Isometric handgrip strength
IL	Interleukin
MaSS	Maastricht Sarcopenia study
MCP1	Monocyte chemoattractant protein 1
MDVs	Mitochondrial-derived vesicles
MIP1α	Macrophage inflammatory protein 1α
MPO	Myeloperoxidase
MRI	Magnetic resonance imaging
PDGF-BB	Platelet-derived growth factor-BB
PF&S	Physical frailty and sarcopenia
PLS-DA	Partial Least Squares–Discriminant Analysis
SASP	Senescence-associated secretory phenotype
SCFAs	Short chain fatty acids
SPRINTT	Sarcopenia and Physical fRailty IN older people: multi-componenT Treatment strategies
sEVs	Small extracellular vesicle
SO-CovSel	Sequential and Orthogonalized Covariance Selection
SPPB	Short physical performance battery