Table 3.
Semaphorins in diabetic complications.
| Diabetic Complications | Semaphorins Involved | Receptors Involved | References |
|---|---|---|---|
| Diabetic retinopathy | Sema4D | PlexinB1 | [96] |
| Sema3A | Nrp1 | [97,98,99,100] | |
| Sema3E | PlexinD1 | [101] | |
| Diabetic nephropathy | Sema3A | Nrp1, PlexinA1 | [97,102,103,104] |
| Sema3E | Not mentioned | [105] | |
| Sema3G | Not mentioned | [105,106] | |
| Sema5A, Sema5E | Not mentioned | [105] | |
| Sema6D | Not mentioned | [107] | |
| Diabetic neuropathy | Sema3C | Nrp1, Nrp2 | [108,109] |
| Sema3A | Not mentioned | [110,111] | |
| Sema6A | Not mentioned | [112] | |
| Diabetic wound healing | Sema4D | PlexinB2 | [113] |
| Sema6A | Not mentioned | [114] | |
| Diabetic osteoporosis | Sema3A | Not mentioned | [115,116,117,118] |