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Interaction of PMTPV with ECL2 of CLDN1. (A) Scheme for the coating of biotin and biotin-fused ECL2 of CLDN1 on the sensor chip. (B) The QCM frequency was measured every 1 s. Then, 5 ng/mL PMTPV was applied at the time period indicated by the hatched box. Bovine serum albumin (BSA) was used as a non-specific protein for a negative control.
