Figure 4.

Effects of PADI2 knockout on the relative expression levels of the activated caspase-3, -2, -8, and -9. In the differentiated macrophages stimulated with LPS, the protein expression levels of the intact caspases and the cleaved caspases were performed by Western blotting in the PADI2 knockout group and the control group. The relative protein expression was defined as the ratio of intact caspases or cleaved caspases to the actin band intensity: (A) caspase-3; (B) caspase-2; (C) caspase-8; (D) caspase-9.