Table 2.
miRNA | Target Molecule | Related Skin Diseases | Reference | |
---|---|---|---|---|
Change | Name | |||
↓ | miR-125b | FGFR2 | Psoriasis | [46] |
AKT3 | [47] | |||
miR-181b-5p | AKT3, TRL4 | [47,48] | ||
miR-520a | AKT | [49] | ||
miR-320b | AKT3 | [50] | ||
miR-194 | GRHL2 | [51] | ||
miR-217 | [52] | |||
miR-138 | hTERT | [53] | ||
miR-150 | HIF-1α, VEGFA | [54] | ||
miR-145-5p | MLK3 | [55] | ||
miR-20a-3p | SFMBT1 | [56] | ||
miR-876-5p | ANG-1 | [57] | ||
miR-99a | FZD5/FZD8 | [58] | ||
miR-187 | CD276 | [59] | ||
miR-548a-3p | PPP3R1 | [60] | ||
miR-330 | CTNNB1 | [61] | ||
miR-146a | EGFR | Psoriasis, cSCC | [62,63] | |
miR-96-5p | BNP3 | Wound healing | [64] | |
miR-181a | KRAS | cSCC | [29] | |
miR-99b | IGF-1R | Condyloma acuminatum | [65] | |
miR-203 | ΔNp63 | Epidermodysplasia verruciformis | [66] | |
↑ | miR-21 | Caspase 8 | Psoriasis | [67,68] |
Wound healing | [69,70] | |||
MSH2 | cSCC | [71] | ||
miR-31 | PPP6C | Psoriasis | [72] | |
LATS2 | [73] | |||
EMP-1 | Wound healing | [74] | ||
RASA1 | [75] | |||
SPRED1 | ||||
SPRED2 | ||||
SPRY4 | ||||
RhoTB1 | cSCC | [76] | ||
miR-744-3p | KLLN | Psoriasis | [77] | |
miR-17-92 | CDKN2B | [78] | ||
miR-130a | STK40 | [79] | ||
miR-122-5p | SPRY2 | [80] | ||
miR-223 | PTEN | [81] | ||
miR-17-3p | MYOT | Wound healing | [82] | |
miR-126 | PLK2 | [83] |
↑: upregulation, ↓: downregulation.